Streptococcus pneumoniae: does antimicrobial resistance matter?

JP Lynch, GG Zhanel - Seminars in Respiratory and Critical …, 2009 - thieme-connect.com
Over the past 3 decades, antimicrobial resistance among Streptococcus pneumoniae, the
most common cause of community-acquired pneumonia (CAP), has escalated dramatically …

[HTML][HTML] Streptococcus pneumoniae: the evolution of antimicrobial resistance to beta-lactams, fluoroquinolones and macrolides

JE Cornick, SD Bentley - Microbes and infection, 2012 - Elsevier
Multi drug resistant Streptococcus pneumoniae constitute a major public health concern
worldwide. In this review we discuss how the transformable nature of the pneumococcus, in …

The macrolide antibiotics: a pharmacokinetic and pharmacodynamic overview

R Jain, LH Danziger - Current pharmaceutical design, 2004 - ingentaconnect.com
The macrolide antimicrobial family is a comprised of 14, 15 and 16 member-ringed
compounds that are characterized by similar chemical structures, mechanisms of action and …

[HTML][HTML] A Case of In Situ Phage Therapy against Staphylococcus aureus in a Bone Allograft Polymicrobial Biofilm Infection: Outcomes and Phage-Antibiotic …

B Van Nieuwenhuyse, C Galant, B Brichard… - Viruses, 2021 - mdpi.com
Phage therapy (PT) shows promising potential in managing biofilm infections, which include
refractory orthopedic infections. We report the case of a 13-year-old girl who developed …

[HTML][HTML] Composite mobile genetic elements disseminating macrolide resistance in Streptococcus pneumoniae

ST Chancey, S Agrawal, MR Schroeder… - Frontiers in …, 2015 - frontiersin.org
Macrolide resistance in Streptococcus pneumoniae emerged in the US and globally during
the early 1990's. The RNA methylase encoded by erm (B) and the macrolide efflux genes …

Dynamics of antibiotic resistance genes and presence of putative pathogens during ambient temperature anaerobic digestion

JA Resende, CG Diniz, VL Silva… - Journal of applied …, 2014 - academic.oup.com
Aims This study was focused on evaluating the persistency of antimicrobial resistance (AR)
genes and putative pathogenic bacteria in an anaerobic digesters operating at mesophilic …

Escalation of antimicrobial resistance among Streptococcus pneumoniae: implications for therapy

JP Lynch, GG Zhanel - Seminars in respiratory and critical care …, 2005 - thieme-connect.com
Over the past 2 decades, antimicrobial resistance among Streptococcus pneumoniae, the
most common cause of community-acquired pneumonia (CAP), has escalated dramatically …

Assessment of long-term macrolide exposure on the oropharyngeal microbiome and macrolide resistance in healthy adults and consequences for onward …

LD Burr, SL Taylor, A Richard, V Schreiber… - Antimicrobial agents …, 2022 - Am Soc Microbiol
While the use of long-term macrolide therapy to prevent exacerbations in chronic respiratory
diseases is widespread, its impact on the oropharyngeal microbiota and macrolide …

Expression of resistance genes instead of gene abundance are correlated with trace levels of antibiotics in urban surface waters

X Yi, C Lin, EJL Ong, M Wang, B Li, Z Zhou - Environmental Pollution, 2019 - Elsevier
In this study, antibiotic resistance to macrolide-lincosamide-streptogramin B (MLS B)
antibiotics in total microbial community in surface water in a coastal urban city was …

[HTML][HTML] Genomic Epidemiology of Streptococcus suis Sequence Type 7 Sporadic Infections in the Guangxi Zhuang Autonomous Region of China

M Wang, P Du, J Wang, R Lan, J Huang, M Luo… - Pathogens, 2019 - mdpi.com
Streptococcus suis is an important zoonotic pathogen. Serotype 2 and sequence type (ST) 1
are the most frequently reported strains in both infected humans and pigs. ST7 is only …