The blood coagulation protein fibrinogen is deposited in the brain in a wide range of
neurological diseases and traumatic injuries with blood–brain barrier (BBB) disruption …

Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …

The interaction of coagulation factors with the perivascular environment affects the
development of disease in ways that extend beyond their traditional roles in the acute …

Damage‐associated molecular patterns (DAMPs) include endogenous intracellular
molecules released by activated or necrotic cells and extracellular matrix (ECM) molecules …

Microglia are long-living resident immune cells of the brain, which secure a stable chemical
and physical microenvironment necessary for the proper functioning of the central nervous …

Epilepsy is one of the most common chronic neurologic diseases, yet approximately one-
third of affected patients do not respond to anticonvulsive drugs that target neurons or …

The blood–brain barrier (BBB) is formed primarily to protect the brain microenvironment from
the influx of plasma components, which may disturb neuronal functions. The BBB is a …

Integrins are critical for the migration and function of leukocytes in inflammation. However,
the interaction between integrin αM (CD11b), which has high expression in monocytes and …

Scar formation in the nervous system begins within hours after traumatic injury and is
characterized primarily by reactive astrocytes depositing proteoglycans that inhibit …

The existence of extracellular DNA in human plasma, also known as cell‐free DNA (cf DNA),
was first described in the 1940s. In recent years, there has been a resurgence of interest in …