[HTML][HTML] Adverse events, side effects and complications in mesenchymal stromal cell-based therapies

DS Baranovskii, ID Klabukov… - Stem Cell …, 2022 - ncbi.nlm.nih.gov
Numerous clinical studies have shown a wide clinical potential of mesenchymal stromal
cells (MSCs) application. However, recent experience has accumulated numerous reports of …

Optimization of mesenchymal stromal cell (MSC) manufacturing processes for a better therapeutic outcome

ME Fernández-Santos, M Garcia-Arranz… - Frontiers in …, 2022 - frontiersin.org
MSCs products as well as their derived extracellular vesicles, are currently being explored
as advanced biologics in cell-based therapies with high expectations for their clinical use in …

[HTML][HTML] Mesenchymal stromal/stem cells spheroid culture effect on the therapeutic efficacy of these cells and their exosomes: A new strategy to overcome cell therapy …

A Hazrati, K Malekpour, S Soudi… - Biomedicine & …, 2022 - Elsevier
Cell therapy is one of the new treatment methods in which mesenchymal stem/stromal cell
(MSCs) transplantation is one of the cells widely used in this field. The results of MSCs …

iPSC-derived mesenchymal stem cells attenuate cerebral ischemia-reperfusion injury by inhibiting inflammatory signaling and oxidative stress

M Arakawa, Y Sakamoto, Y Miyagawa, C Nito… - … Therapy-Methods & …, 2023 - cell.com
Induced pluripotent stem cell-derived mesenchymal stem cells (iMSCs) hold great promise
as a cell source for transplantation into injured tissues to alleviate inflammation. However …

Optimization of human umbilical cord blood-derived mesenchymal stem cell isolation and culture methods in serum-and xeno-free conditions

LT Nguyen, NT Tran, UTT Than, MQ Nguyen… - Stem cell research & …, 2022 - Springer
Background Although umbilical cord blood (UCB) is identified as a source of mesenchymal
stem cells (MSCs) with various advantages, the success in cell isolation is volatile …

Isolation, culture, and delivery considerations for the use of mesenchymal stem cells in potential therapies for acute liver failure

H Yang, J Chen, J Li - Frontiers in Immunology, 2023 - frontiersin.org
Acute liver failure (ALF) is a high-mortality syndrome for which liver transplantation is
considered the only effective treatment option. A shortage of donor organs, high costs and …

The interplay between extracellular matrix and progenitor/stem cells during wound healing: Opportunities and future directions

M Rasouli, A Rahimi, M Soleimani - Acta Histochemica, 2021 - Elsevier
Skin wound healing, a dynamic physiological process, progresses through coordinated
overlapping phases to restore skin integrity. In some pathological conditions such as …

Serum-free cultures: could they be a future direction to improve neuronal differentiation of mesenchymal stromal cells?

G Schepici, A Gugliandolo, E Mazzon - International journal of molecular …, 2022 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are undifferentiated cells with multilinear potential,
known for their immunomodulatory and regenerative properties. Although the scientific …

Scaling up stem cell production: harnessing the potential of microfluidic devices

L Ding, S Oh, J Shrestha, A Lam, Y Wang… - Biotechnology …, 2023 - Elsevier
Stem cells are specialised cells characterised by their unique ability to both self-renew and
transform into a wide array of specialised cell types. The widespread interest in stem cells for …

Regulation of self-renewal and senescence in primitive mesenchymal stem cells by Wnt and TGFβ signaling

M Mazzella, K Walker, C Cormier… - Stem Cell Research & …, 2023 - Springer
Background The therapeutic application of multipotent mesenchymal stem cells (MSCs)
encounters significant challenges, primarily stemming from their inadequate growth and …