Combining experimental evolution with next-generation sequencing: a powerful tool to study adaptation from standing genetic variation
Evolve and resequence (E&R) is a new approach to investigate the genomic responses to
selection during experimental evolution. By using whole genome sequencing of pools of …
selection during experimental evolution. By using whole genome sequencing of pools of …
What genomic data can reveal about eco-evolutionary dynamics
Recognition that evolution operates on the same timescale as ecological processes has
motivated growing interest in eco-evolutionary dynamics. Nonetheless, generating sufficient …
motivated growing interest in eco-evolutionary dynamics. Nonetheless, generating sufficient …
Genetic redundancy fuels polygenic adaptation in Drosophila
The genetic architecture of adaptive traits is of key importance to predict evolutionary
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …
responses. Most adaptive traits are polygenic—ie, result from selection on a large number of …
Estimating the genome-wide contribution of selection to temporal allele frequency change
Rapid phenotypic adaptation is often observed in natural populations and selection
experiments. However, detecting the genome-wide impact of this selection is difficult since …
experiments. However, detecting the genome-wide impact of this selection is difficult since …
Selective trade-offs maintain alleles underpinning complex trait variation in plants
To understand evolutionary factors that maintain complex trait variation, we sequenced
genomes from a single population of the plant Mimulus guttatus, identifying hundreds of …
genomes from a single population of the plant Mimulus guttatus, identifying hundreds of …
Select and resequence reveals relative fitness of bacteria in symbiotic and free-living environments
Assays to accurately estimate relative fitness of bacteria growing in multistrain communities
can advance our understanding of how selection shapes diversity within a lineage. Here, we …
can advance our understanding of how selection shapes diversity within a lineage. Here, we …
Patterns of Linkage Disequilibrium and Long Range Hitchhiking in Evolving Experimental Drosophila melanogaster Populations
SU Franssen, V Nolte, R Tobler… - Molecular biology and …, 2015 - academic.oup.com
Whole-genome resequencing of experimental populations evolving under a specific
selection regime has become a popular approach to determine genotype–phenotype maps …
selection regime has become a popular approach to determine genotype–phenotype maps …
Pervasive Linked Selection and Intermediate-Frequency Alleles Are Implicated in an Evolve-and-Resequencing Experiment of Drosophila simulans
Abstract Evolve-and-Resequence (E&R) experiments, where researchers allow populations
to evolve within one or more controlled environments and then whole-genome sequence the …
to evolve within one or more controlled environments and then whole-genome sequence the …
The genetic architecture of temperature adaptation is shaped by population ancestry and not by selection regime
Background Understanding the genetic architecture of temperature adaptation is key for
characterizing and predicting the effect of climate change on natural populations. One …
characterizing and predicting the effect of climate change on natural populations. One …
Whole-Genome Resequencing of Experimental Populations Reveals Polygenic Basis of Egg-Size Variation in Drosophila melanogaster
Complete genome resequencing of populations holds great promise in deconstructing
complex polygenic traits to elucidate molecular and developmental mechanisms of …
complex polygenic traits to elucidate molecular and developmental mechanisms of …