Importance Schizophrenia is a common, severe mental illness that most clinicians will
encounter regularly during their practice. This report provides an overview of the clinical …

Abstract Purpose of Review We review recent developments on risk factors in
schizophrenia. Recent Findings The way we think about schizophrenia today is profoundly …

Glutamate and dopamine systems play distinct roles in terms of neuronal signalling, yet both
have been proposed to contribute significantly to the pathophysiology of schizophrenia. In …

Economics and mental health are intertwined. Apart from the accumulating evidence of the
huge economic impacts of mental ill‐health, and the growing recognition of the effects that …

Psychosis is a heterogeneous psychiatric condition for which a multitude of risk and
protective factors have been suggested. This umbrella review aimed to classify the strength …

Adolescents are often described as a strange and different species that behaves like no
other age group, typical behaviours being excessive risk-taking and sensitivity to peer …

At its re-birth 30 years ago, the neurodevelopment hypothesis of schizophrenia focussed on
aberrant genes and early neural hazards, but then it grew to include ideas concerning …

BackgroundThe aims of this meta-analysis are (i) to estimate the pooled relative risk (RR) of
developing non-affective psychotic disorder (NAPD) and affective psychotic disorder (APD) …

Blood–brain barrier pathology is recognised as a central factor in the development of many
neurological disorders, but much less is known about the role of the blood–brain barrier in …

BackgroundEthnic minority groups in Western countries face an increased risk of psychotic
disorders. Causes of this long-standing public health inequality remain poorly understood …