Unravelling mechanisms of bacterial recognition by Acanthamoeba: insights into microbial ecology and immune responses

F Nasher, BW Wren - Frontiers in Microbiology, 2024 - frontiersin.org
Acanthamoeba, are ubiquitous eukaryotic microorganisms, that play a pivotal role in
recognizing and engulfing various microbes during predation, offering insights into microbial …

[HTML][HTML] BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus

HC Chuang, MH Chen, YM Chen, HY Yang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Background: Serum-derived exosomes are correlated with disease severity of human
systemic lupus erythematosus (SLE). The proteins in the T-cell-derived exosomes from SLE …

Scorpionfish BPI is highly active against multiple drug-resistant Pseudomonas aeruginosa isolates from people with cystic fibrosis

JM Holzinger, M Toelge, M Werner, KU Ederer… - Elife, 2023 - elifesciences.org
Chronic pulmonary infection is a hallmark of cystic fibrosis (CF) and requires continuous
antibiotic treatment. In this context, Pseudomonas aeruginosa (Pa) is of special concern …

[HTML][HTML] Genome-wide association and functional genomic analyses for various hoof health traits in North American Holstein cattle

LPBS Junior, LFB Pinto, VAR Cruz, GA Oliveira Jr… - Journal of Dairy …, 2024 - Elsevier
Hoof diseases are a major welfare and economic issue in the global dairy cattle production
industry, which can be minimized through improved management and breeding practices …

Mammals' humoral immune proteins and peptides targeting the bacterial envelope: from natural protection to therapeutic applications against multidrug‐resistant …

M Escobar‐Salom, G Torrens… - Biological …, 2022 - Wiley Online Library
Mammalian innate immunity employs several humoral 'weapons' that target the bacterial
envelope. The threats posed by the multidrug‐resistant 'ESKAPE'Gram‐negative pathogens …

BPI23-Fcγ alleviates lethal multi-drug-resistant Acinetobacter baumannii infection by enhancing bactericidal activity and orchestrating neutrophil function

Y Wang, Q Kong, Q Zhang, T Ma, Y An, Y Zhou… - International Journal of …, 2024 - Elsevier
Antibiotic resistance has become a major threat, contributing significantly to morbidity and
mortality globally. Administering non-antibiotic therapy, such as antimicrobial peptides, is …

Bactericidal/permeability-increasing protein downregulates the inflammatory response in in vivo models of arthritis

A Scanu, R Luisetto, F Oliviero, F Galuppini… - International Journal of …, 2022 - mdpi.com
We investigated the effects of bactericidal/permeability-increasing protein (BPI) alone or in
combination with hyaluronic acid (HA) in two animal models: collagen-induced arthritis (CIA) …

Host Defense Proteins and Peptides with Lipopolysaccharide-Binding Activity from Marine Invertebrates and Their Therapeutic Potential in Gram-Negative Sepsis

TF Solov'eva, SI Bakholdina, GA Naberezhnykh - Marine Drugs, 2023 - mdpi.com
Sepsis is a life-threatening complication of an infectious process that results from the
excessive and uncontrolled activation of the host's pro-inflammatory immune response to a …

Bactericidal Permeability-Increasing Protein (BPI) Inhibits Mycobacterium tuberculosis Growth

S Guzmán-Beltrán, E Juárez, BL Cruz-Muñoz… - Biomolecules, 2024 - mdpi.com
Bactericidal permeability-increasing protein (BPI) is a multifunctional cationic protein
produced by neutrophils, eosinophils, fibroblasts, and macrophages with antibacterial anti …

[PDF][PDF] 脂多糖结合蛋白和杀菌/通透性增加蛋白: 脓毒症的潜在治疗靶点

杨泽, 王可洲, 于杨 - 中国比较医学杂志, 2022 - zgbjyx.cnjournals.com
脂多糖结合蛋白和杀菌/ 通透性增加蛋白:脓毒症的潜在治疗靶点 Page 1 2022 年11 月 第32 卷第11
期 中国比较医学杂志 CHINESE JOURNAL OF COMPARATIVE MEDICINE November, 2022 Vol …