Diagnostic performance of metagenomic next-generation sequencing for Pneumocystis jirovecii pneumonia

X Li, Z Li, J Ye, W Ye - BMC Infectious Diseases, 2023 - Springer
Objective Pneumocystis jirovecii pneumonia (PJP) can be a life-threatening opportunistic
infection. We aimed to evaluate the diagnostic accuracy of metagenomic next-generation …

[HTML][HTML] Transmission and colonization of Pneumocystis jirovecii

C Vera, ZV Rueda - Journal of Fungi, 2021 - mdpi.com
Pneumocystis spp. was discovered in 1909 and was classified as a fungus in 1988. The
species that infects humans is called P. jirovecii and important characteristics of its genome …

Of mycelium and men: inherent human susceptibility to fungal diseases

DC Vinh - Pathogens, 2023 - mdpi.com
In medical mycology, the main context of disease is iatrogenic-based disease. However,
historically, and occasionally, even today, fungal diseases affect humans with no obvious …

Fungal genomics in respiratory medicine: what, how and when?

AP Brackin, SJ Hemmings, MC Fisher, J Rhodes - Mycopathologia, 2021 - Springer
Respiratory infections caused by fungal pathogens present a growing global health concern
and are a major cause of death in immunocompromised patients. Worryingly, coronavirus …

Pneumocystis mating-type locus and sexual cycle during infection

PM Hauser - Microbiology and Molecular Biology Reviews, 2021 - Am Soc Microbiol
Pneumocystis species colonize mammalian lungs and cause deadly pneumonia if the
immune system of the host weakens. Each species presents a specificity for a single …

Decades-old studies of fungi associated with mammalian lungs and modern DNA sequencing approaches help define the nature of the lung mycobiome

PS Hamm, JW Taylor, JA Cook, DO Natvig - PLoS pathogens, 2020 - journals.plos.org
The vertebrate lung is the organ with the largest surface area presented to the external
environment. The combined alveolar surface area of both adult human lungs is about 100 …

Point-Counterpoint: Should Serum β-d-Glucan Testing Be Used for the Diagnosis of Pneumocystis jirovecii Pneumonia?

G Corsi-Vasquez, L Ostrosky-Zeichner… - Journal of Clinical …, 2019 - Am Soc Microbiol
INTRODUCTION Despite the widespread use of prophylactic antibiotics in high-risk
individuals, Pneumocystis jirovecii remains an important cause of pneumonia in …

Revisiting the Pneumocystis host specificity paradigm and transmission ecology in wild Southeast Asian rodents

A Latinne, HW Chen, CC Kuo, R Lorica… - Infection, Genetics and …, 2021 - Elsevier
Pneumocystis fungi are opportunistic parasites of mammalian lungs whose evolution,
ecology and host specificity in natural host populations remain poorly understood and …

Humans are selectively exposed to pneumocystis jirovecii

OH Cissé, L Ma, C Jiang, M Snyder, JA Kovacs - Mbio, 2020 - Am Soc Microbiol
Environmental exposure has a significant impact on human health. While some airborne
fungi can cause life-threatening infections, the impact of environment on fungal spore …

Evolutionary history of Pneumocystis fungi in their African rodent hosts

J Petružela, J Bryja, A Bryjová, A Katakweba… - Infection, Genetics and …, 2019 - Elsevier
Pneumocystis is a genus of parasitic fungi infecting lung tissues in a wide range of mammal
species, displaying a strong host specificity and patterns of co-speciation with their hosts …