Next-generation, personalised, model-based critical care medicine: a state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to …
JG Chase, JC Preiser, JL Dickson, A Pironet… - Biomedical engineering …, 2018 - Springer
Critical care, like many healthcare areas, is under a dual assault from significantly
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …
increasing demographic and economic pressures. Intensive care unit (ICU) patients are …
Toward nutrition improving outcome of critically ill patients: How to interpret recent feeding RCTs?
J Gunst, MP Casaer, JC Preiser, J Reignier… - Critical Care, 2023 - Springer
Although numerous observational studies associated underfeeding with poor outcome,
recent randomized controlled trials (RCTs) have shown that early full nutritional support …
recent randomized controlled trials (RCTs) have shown that early full nutritional support …
Higher glycemic variability within the first day of ICU admission is associated with increased 30-day mortality in ICU patients with sepsis
WC Chao, CH Tseng, CL Wu, SJ Shih, CY Yi… - Annals of intensive …, 2020 - Springer
Background High glycemic variability (GV) is common in critically ill patients; however, the
prevalence and mortality association with early GV in patients with sepsis remains unclear …
prevalence and mortality association with early GV in patients with sepsis remains unclear …
Digital twins and automation of care in the intensive care unit
Healthcare is under increasing demand pressure as societies age and expectations rise,
multiplied by increasing incidence of chronic diseases and decreasing available funding …
multiplied by increasing incidence of chronic diseases and decreasing available funding …
Glycemic control in the intensive care unit: a control systems perspective
Computers and automation have revolutionised quality and productivity in many industries,
but not in medicine. Healthcare costs are thus growing beyond the ability of society to pay for …
but not in medicine. Healthcare costs are thus growing beyond the ability of society to pay for …
Improving glycemic control in critically ill patients: personalized care to mimic the endocrine pancreas
There is considerable physiological and clinical evidence of harm and increased risk of
death associated with dysglycemia in critical care. However, glycemic control (GC) currently …
death associated with dysglycemia in critical care. However, glycemic control (GC) currently …
Association between dysglycemia and mortality by diabetes status and risk factors of dysglycemia in critically ill patients: a retrospective study
H Ma, G Yu, Z Wang, P Zhou, W Lv - Acta Diabetologica, 2022 - Springer
Aims Dysglycemia, including the three domains hyperglycemia, hypoglycemia, and
increased glycemic variability (GV), is associated with high mortality among critically ill …
increased glycemic variability (GV), is associated with high mortality among critically ill …
Effect of glycemic gap upon mortality in critically ill patients with diabetes
R Lou, L Jiang, B Zhu - Journal of Diabetes Investigation, 2021 - Wiley Online Library
Abstract Aims/Introduction Hyperglycemia, hypoglycemia, and blood glucose fluctuation are
associated with the outcome in critically ill patients, but the target of blood glucose control is …
associated with the outcome in critically ill patients, but the target of blood glucose control is …
Incorporating real-world evidence into the development of patient blood glucose prediction algorithms for the ICU
O Fitzgerald, O Perez-Concha, B Gallego… - Journal of the …, 2021 - academic.oup.com
Objective Glycemic control is an important component of critical care. We present a data-
driven method for predicting intensive care unit (ICU) patient response to glycemic control …
driven method for predicting intensive care unit (ICU) patient response to glycemic control …
Glycemic control with insulin attenuates sepsis-associated encephalopathy by inhibiting glial activation via the suppression of the nuclear factor kappa B and mitogen …
CT Huang, JH Lue, TH Cheng, YJ Tsai - Brain Research, 2020 - Elsevier
Sepsis-associated encephalopathy (SAE) is frequently encountered in critically ill patients.
Hyperglycemia is a common phenomenon among patients with sepsis, and glycemic control …
Hyperglycemia is a common phenomenon among patients with sepsis, and glycemic control …