Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

Multi-target drugs against selective multiple targets improve therapeutic efficacy, safety and
resistance profiles by collective regulations of a primary therapeutic target together with …

Multi-target drugs against particular multiple targets get better protection, resistance profiles
and curative influence by cooperative rules of a key beneficial target with resistance …

Several pathogen parasite species show different susceptibilities to different antiparasite
drugs. Unfortunately, almost all structure-based methods are one-task or one-target …

There are many of pathogen parasite species with different susceptibility profile to
antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of …

This review article is, in a way, different from traditional review articles in that, besides being
informative and reporting on the past published work in the area of graphical representation …

Antimicrobial peptides (AMPs) represent promising alternatives to fight against bacterial
pathogens. However, cellular toxicity remains one of the main concerns in the early …

The method MARCH-INSIDE (MARkovian CHemicals IN SIlico DEsign) is a simple but
efficient computational approach to the study of Quantitative Structure-Activity Relationships …

Prediction of polypharmacology of known drugs and new molecules against selected
multiple targets is highly useful for finding new therapeutic applications of existing drugs …

One limitation of almost all antiviral Quantitative Structure–Activity Relationships (QSAR)
models is that they predict the biological activity of drugs against only one species of virus …