Focus on the glycerophosphocholine pathway in choline phospholipid metabolism of cancer
Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …
The relayed nuclear Overhauser effect in magnetization transfer and chemical exchange saturation transfer MRI
Magnetic resonance (MR) is a powerful technique for noninvasively probing molecular
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …
species in vivo but suffers from low signal sensitivity. Saturation transfer (ST) MRI …
Review and consensus recommendations on clinical APT‐weighted imaging approaches at 3T: application to brain tumors
Amide proton transfer‐weighted (APTw) MR imaging shows promise as a biomarker of brain
tumor status. Currently used APTw MRI pulse sequences and protocols vary substantially …
tumor status. Currently used APTw MRI pulse sequences and protocols vary substantially …
Ceramic resonators for targeted clinical magnetic resonance imaging of the breast
A Shchelokova, V Ivanov, A Mikhailovskaya… - Nature …, 2020 - nature.com
Currently, human magnetic resonance (MR) examinations are becoming highly specialized
with a pre-defined and often relatively small target in the body. Conventionally, clinical MR …
with a pre-defined and often relatively small target in the body. Conventionally, clinical MR …
Assignment of molecular origins of NOE signal at− 3.5 ppm in the brain
Purpose Nuclear Overhauser enhancemen mediated saturation transfer effect, termed NOE
(− 3.5 ppm), is a major source of CEST MRI contrasts at 3.5 ppm in the brain. Previous …
(− 3.5 ppm), is a major source of CEST MRI contrasts at 3.5 ppm in the brain. Previous …
CEST‐MRI for body oncologic imaging: are we there yet?
E Vinogradov, J Keupp, IE Dimitrov, S Seiler… - NMR in …, 2023 - Wiley Online Library
Chemical exchange saturation transfer (CEST) MRI has gained recognition as a valuable
addition to the molecular imaging and quantitative biomarker arsenal, especially for …
addition to the molecular imaging and quantitative biomarker arsenal, especially for …
Breast amide proton transfer imaging at 3 T: diagnostic performance and association with pathologic characteristics
Z Liu, J Wen, M Wang, Y Ren, Q Yang… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Amide proton transfer (APT) imaging has been increasingly applied in tumor
characterization. However, its value in evaluating breast cancer remains undetermined …
characterization. However, its value in evaluating breast cancer remains undetermined …
Detection of tissue pH with quantitative chemical exchange saturation transfer magnetic resonance imaging
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) has
emerged as a novel means for sensitive detection of dilute labile protons and chemical …
emerged as a novel means for sensitive detection of dilute labile protons and chemical …
A novel normalization for amide proton transfer CEST MRI to correct for fat signal–induced artifacts: application to human breast cancer imaging
F Zimmermann, A Korzowski, J Breitling… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose The application of amide proton transfer (APT) CEST MRI for diagnosis of breast
cancer is of emerging interest. However, APT imaging in the human breast is affected by the …
cancer is of emerging interest. However, APT imaging in the human breast is affected by the …
Breast cancer imaging with glucosamine CEST (chemical exchange saturation transfer) MRI: first human experience
Objectives This study aims to evaluate the feasibility of imaging breast cancer with
glucosamine (GlcN) chemical exchange saturation transfer (CEST) MRI technique to …
glucosamine (GlcN) chemical exchange saturation transfer (CEST) MRI technique to …