Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs)
are widely expressed and have key roles in gene regulation. Recent studies have begun to …

It is increasingly evident that many of the genomic mutations in cancer reside inside regions
that do not encode proteins. However, these regions are often transcribed into long …

Understanding the complex and specific roles played by non-coding RNAs (ncRNAs), which
comprise the bulk of the genome, is important for understanding virtually every hallmark of …

The deeper understanding of non-coding RNAs has recently changed the dogma of
molecular biology assuming protein-coding genes as unique functional biological effectors …

Immune dysregulation plays a vital role in colorectal cancer initiation and progression. Long
noncoding RNAs (lncRNA) exhibit multiple functions including regulation of gene …

Liver cancer stem cells (CSCs) may contribute to the high rate of recurrence and
heterogeneity of hepatocellular carcinoma (HCC). However, the biology of hepatic CSCs …

Wnt signaling transduces evolutionarily conserved pathways which play important roles in
initiating and regulating a diverse range of cellular activities, including cell proliferation …

Objective Long non-coding RNAs (lncRNAs) are emerging as key molecules in cancers, yet
their potential molecular mechanisms are not well understood. The objective of this study is …

Background Recent evidences showed that long noncoding RNAs (lncRNAs) are frequently
dysregulated and play important roles in various cancers. Clear cell renal cell carcinoma …

Long non-coding RNA (lncRNA), which is a kind of noncoding RNA, is generally
characterized as being more than 200 nucleotide transcripts in length. LncRNAs exhibit …