The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …

Collagen-based devices, in various physical conformations, are extensively used for tissue
engineering and regenerative medicine applications. Given that the natural cross-linking …

Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

The management of complex abdominal problems with the open-abdomen and temporary
abdominal closure techniques has become a common and valuable tool in surgery …

Background Repair of contaminated abdominal wall defects entails the dilemma of choosing
between synthetic material, with its presumed risk of surgical site complications, and biologic …

Background: A variety of mesh materials are available for ventral hernia repair (VHR), each
with a unique set of characteristics. Surgeons are offered an ever-expanding selection of …

Purpose The use of mesh is a common practice in ventral hernia repair (VHR). Lack of
consensus on which prosthetic material works better in different settings remains. This meta …

The clinical use of biological scaffold materials has become commonplace. Such scaffolds
are composed of extracellular matrix (ECM), or components of ECM, derived from allogeneic …

Background The current standard of treatment for most ventral hernias is a mesh-based
repair. Little is known about the safety and efficacy of biologic versus nonbiologic grafts. A …

Implantation of surgical meshes composed of synthetic and biological materials has been
applied for abdominal wall defect repair. Despite many efforts, there are no reliable meshes …