The power of imaging to understand extracellular vesicle biology in vivo

FJ Verweij, L Balaj, CM Boulanger, DRF Carter… - Nature …, 2021 - nature.com
Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every
cell type. EVs have diverse biological activities, ranging from roles in development and …

Molecular probes for autofluorescence-free optical imaging

Y Jiang, K Pu - Chemical reviews, 2021 - ACS Publications
Optical imaging is an indispensable tool in clinical diagnostics and fundamental biomedical
research. Autofluorescence-free optical imaging, which eliminates real-time optical …

Engineered exosomes from different sources for cancer-targeted therapy

M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …

Emerging prospects of exosomes for cancer treatment: from conventional therapy to immunotherapy

GH Nam, Y Choi, GB Kim, S Kim, SA Kim… - Advanced …, 2020 - Wiley Online Library
Exosomes are a class of extracellular vesicles of around 100 nm in diameter that are
secreted by most cells and contain various bioactive molecules reflecting their cellular origin …

Molecular substrates for the construction of afterglow imaging probes in disease diagnosis and treatment

X Wang, K Pu - Chemical Society Reviews, 2023 - pubs.rsc.org
Afterglow, an intrinsic phenomenon of persistent luminescence emitted from chemical
defects after light irradiation, has shown tremendous promise for applications in bioimaging …

Near-Infrared Afterglow Luminescence of Chlorin Nanoparticles for Ultrasensitive In Vivo Imaging

W Chen, Y Zhang, Q Li, Y Jiang, H Zhou… - Journal of the …, 2022 - ACS Publications
Afterglow imaging holds great potential for ultrasensitive biomedical imaging. As it detects
photons after the cessation of real-time light excitation, autofluorescence can therefore be …

Optogenetic tools for subcellular applications in neuroscience

BR Rost, F Schneider-Warme, D Schmitz, P Hegemann - Neuron, 2017 - cell.com
The ability to study cellular physiology using photosensitive, genetically encoded molecules
has profoundly transformed neuroscience. The modern optogenetic toolbox includes …

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

CP Lai, EY Kim, CE Badr, R Weissleder… - Nature …, 2015 - nature.com
Accurate spatiotemporal assessment of extracellular vesicle (EV) delivery and cargo RNA
translation requires specific and robust live-cell imaging technologies. Here we engineer …

Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter

CP Lai, O Mardini, M Ericsson, S Prabhakar… - ACS …, 2014 - ACS Publications
Extracellular vesicles (EVs) are nanosized vesicles released by normal and diseased cells
as a novel form of intercellular communication and can serve as an effective therapeutic …

A generic approach towards afterglow luminescent nanoparticles for ultrasensitive in vivo imaging

Y Jiang, J Huang, X Zhen, Z Zeng, J Li, C Xie… - Nature …, 2019 - nature.com
Afterglow imaging with long-lasting luminescence after cessation of light excitation provides
opportunities for ultrasensitive molecular imaging; however, the lack of biologically …