Zero-order drug delivery: State of the art and future prospects

ML Laracuente, HY Marina, KJ McHugh - Journal of Controlled Release, 2020 - Elsevier
Pharmaceutical drugs are an important part of the global healthcare system, with some
estimates suggesting over 50% of the world's population takes at least one medication per …

Recent trends in design and evaluation of chitosan-based colon targeted drug delivery systems: Update 2020

M Kurakula, S Gorityala, K Moharir - Journal of Drug Delivery Science and …, 2021 - Elsevier
Colon-targeted drug delivery systems is an active area of research that is designed to
selectively release the drug in the colonic environment to enhance the oral delivery of active …

[HTML][HTML] Using the intranasal route to administer drugs to treat neurological and psychiatric illnesses: rationale, successes, and future needs

A Lofts, F Abu-Hijleh, N Rigg, RK Mishra, T Hoare - CNS drugs, 2022 - Springer
While the intranasal administration of drugs to the brain has been gaining both research
attention and regulatory success over the past several years, key fundamental and …

Recombinant protein-based injectable materials for biomedical applications

CG Garcia, SS Patkar, B Wang, R Abouomar… - Advanced Drug Delivery …, 2023 - Elsevier
Injectable nanocarriers and hydrogels have found widespread use in a variety of biomedical
applications such as local and sustained biotherapeutic cargo delivery, and as cell …

X-ray imaging for gastrointestinal tracking of microscale oral drug delivery devices

RB Kjeldsen, MN Kristensen, C Gundlach… - ACS Biomaterials …, 2021 - ACS Publications
Microscale devices are promising tools to overcome specific challenges within oral drug
delivery. Despite the availability of advanced high-quality imaging techniques, visualization …

[HTML][HTML] Microfluidic 3D intestine tumor spheroid model for efficient in vitro investigation of nanoparticular formulations

L Elberskirch, T Knoll, R Königsmark, J Renner… - Journal of Drug Delivery …, 2021 - Elsevier
For the treatment of intestinal tumors by oral administration of drugs, the mucus layer of the
intestine represents a barrier, but also a target possibility for drug. The use of nanoparticular …

Supramolecular dendrimers based novel platforms for effective oral delivery of therapeutic moieties

G Fernandes, A Pandey, S Kulkarni, SP Mutalik… - Journal of Drug Delivery …, 2021 - Elsevier
Dendrimers are globular three-dimensional synthetic macromolecules that are highly
branched with a definite molecular weight. The distinct physicochemical properties and …

Hot-melt extrusion–based fused deposition modeling 3D printing of atorvastatin calcium tablets: impact of shape and infill density on printability and performance

P Mandati, N Dumpa, A Alzahrani, D Nyavanandi… - Aaps Pharmscitech, 2022 - Springer
The main objective of the current research was to investigate the effect of tablet shapes
(heart-shaped and round tablets) and infill densities (50% and 100%) on the drug release …

Nanostructured Lipid Carriers for Oral Treatment of Leishmaniasis: Design and Preclinical Evaluation

PJ Rolim Neto, VAW Sales… - Available at SSRN … - papers.ssrn.com
Pentavalent antimonials are the primary treatment for leishmaniasis due to their proven
efficacy and cost-effectiveness. However, they present poor oral absorption, parenteral …