Tree-based QTL mapping with expected local genetic relatedness matrices
Understanding the genetic basis of complex phenotypes is a central pursuit of genetics.
Genome-wide association studies (GWASs) are a powerful way to find genetic loci …
Genome-wide association studies (GWASs) are a powerful way to find genetic loci …
A genealogical estimate of genetic relationships
C Fan, N Mancuso, CWK Chiang - The American Journal of Human …, 2022 - cell.com
The application of genetic relationships among individuals, characterized by a genetic
relationship matrix (GRM), has far-reaching effects in human genetics. However, the current …
relationship matrix (GRM), has far-reaching effects in human genetics. However, the current …
Development of a predictive statistical pharmacological model for local anesthetic agent effects with Bayesian hierarchical model parameter estimation
T Ara, H Kitamura - Medicines, 2023 - mdpi.com
As an alternative to animal use, computer simulations are useful for predicting
pharmacokinetics and cardiovascular activities. For this purpose, we constructed a statistical …
pharmacokinetics and cardiovascular activities. For this purpose, we constructed a statistical …
Genetic characterization of minor carp (Labeo gonius) from Indian rivers revealed through mitochondrial ATPase 6/8 and D-loop region analysis: implications for …
India is the habitat of many freshwater fish species that make a significant contribution to
endemism. However, the native species population is declining at a very fast rate due to …
endemism. However, the native species population is declining at a very fast rate due to …
The big challenge for livestock genomics is to make sequence data pay
M Johnsson - Peer Community Journal, 2023 - peercommunityjournal.org
This paper will argue that one of the biggest challenges for livestock genomics is to make
whole-genome sequencing and functional genomics applicable to breeding practice. It …
whole-genome sequencing and functional genomics applicable to breeding practice. It …
The consequences of mitochondrial T10432C mutation in Cika Cattle: a “Potential” model for Leber's hereditary optic neuropathy
While mitogenome mutations leading to pathological manifestations are rare, more than 200
such mutations have been described in humans. In contrast, pathogenic mitogenome …
such mutations have been described in humans. In contrast, pathogenic mitogenome …
Update on Magellan, the software for the analysis of a single gender lineage in pedigrees
Quantitative genetics is the field of research that links the genetic (DNA) information
(genotype) to the physical traits (phenotype), with the applications in human and livestock …
(genotype) to the physical traits (phenotype), with the applications in human and livestock …
Characterizing the impact of the mutational landscape of SARS-CoV-2 on epitope presentation and CTL
D Hamelin - 2022 - papyrus.bib.umontreal.ca
The current COVID-19 pandemic, caused by Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2), has led to upwards of 6 million deaths and nearly 680 million …
Coronavirus 2 (SARS-CoV-2), has led to upwards of 6 million deaths and nearly 680 million …
Review of the Simulators used in Pharmacology Education and Statistical Models when creating the Simulators
荒敏昭, 喜多村洋幸 - jxiv.jst.go.jp
Animal experiments have long been used as an educational tool in pharmacological
education; however, from the perspective of animal welfare, it is necessary to decrease the …
education; however, from the perspective of animal welfare, it is necessary to decrease the …