MicroRNAs (miRNAs) are crucial post-transcriptional regulators of haematopoietic cell fate
decisions. They act by negatively regulating the expression of key immune development …

Autoimmune diseases are characterized by an exaggerated immune response leading to
damage and dysfunction of specific or multiple organs and tissues. Most autoimmune …

Over the last decade, many epigenetic mechanisms that contribute in the pathogenesis of
autoimmune disorders have been revealed. MicroRNAs (miRNAs) are small, non-coding …

Abstract miRNAs (or microRNAs) are small, endogenous, and noncoding RNAs construct of
about 22 nucleotides. Cumulative evidence from biological experiments shows that miRNAs …

Recent advances in non-protein coding part of human genome analysis have discovered
extensive transcription of large RNA transcripts that lack of coding protein function, termed …

Rheumatoid arthritis (RA) is a polygenic disease characterized by autoimmunity and
systemic inflammation with progressive impairment of joints that results in lifelong disability …

Long noncoding RNA (lncRNA), with size larger than 200 nucleotides, is a new class of
noncoding RNA. Emerging evidence has revealed that lncRNAs play a key role in the …

Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas (CRISPR-
associated) system has been widely explored for the detection of disease-related nucleic …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that affects about 1% of the
world's population. The etiology of RA remains unknown. It is considered to occur in the …

Accumulating evidence indicates that microRNA-146a (miR-146a), a well-known anti-
inflammatory miRNA, acts as a negative feedback regulator of the innate immune response …