FOXP transcription factors in vertebrate brain development, function, and disorders

M Co, AG Anderson, G Konopka - Wiley Interdisciplinary …, 2020 - Wiley Online Library
FOXP transcription factors are an evolutionarily ancient protein subfamily coordinating the
development of several organ systems in the vertebrate body. Association of their genes …

A diagnostic marker to discriminate childhood apraxia of speech from speech delay: I. Development and description of the pause marker

LD Shriberg, EA Strand, M Fourakis, KJ Jakielski… - Journal of Speech …, 2017 - ASHA
Purpose The goal of this article (PM I) is to describe the rationale for and development of the
Pause Marker (PM), a single-sign diagnostic marker proposed to discriminate early or …

[HTML][HTML] MUPET—mouse ultrasonic profile extraction: a signal processing tool for rapid and unsupervised analysis of ultrasonic vocalizations

M Van Segbroeck, AT Knoll, P Levitt, S Narayanan - Neuron, 2017 - cell.com
Vocalizations play a significant role in social communication across species. Analyses in
rodents have used a limited number of spectro-temporal measures to compare ultrasonic …

[HTML][HTML] Arid1b haploinsufficient mice reveal neuropsychiatric phenotypes and reversible causes of growth impairment

C Celen, JC Chuang, X Luo, N Nijem, AK Walker… - elife, 2017 - elifesciences.org
Sequencing studies have implicated haploinsufficiency of ARID1B, a SWI/SNF chromatin-
remodeling subunit, in short stature (Yu et al., 2015), autism spectrum disorder (O'Roak et …

[HTML][HTML] A basal ganglia circuit sufficient to guide birdsong learning

L Xiao, G Chattree, FG Oscos, M Cao, MJ Wanat… - Neuron, 2018 - cell.com
Learning vocal behaviors, like speech and birdsong, is thought to rely on continued
performance evaluation. Whether candidate performance evaluation circuits in the brain are …

[HTML][HTML] Angelman syndrome: from mouse models to therapy

DC Rotaru, EJ Mientjes, Y Elgersma - Neuroscience, 2020 - Elsevier
The UBE3A gene is part of the chromosome 15q11-q13 region that is frequently deleted or
duplicated, leading to several neurodevelopmental disorders (NDD). Angelman syndrome …

[HTML][HTML] USVSEG: A robust method for segmentation of ultrasonic vocalizations in rodents

RO Tachibana, K Kanno, S Okabe, KI Kobayasi… - PloS one, 2020 - journals.plos.org
Rodents' ultrasonic vocalizations (USVs) provide useful information for assessing their
social behaviors. Despite previous efforts in classifying subcategories of time-frequency …

[HTML][HTML] Insights into the neural and genetic basis of vocal communication

G Konopka, TF Roberts - Cell, 2016 - cell.com
The use of vocalizations to communicate information and elaborate social bonds is an
adaptation seen in many vertebrate species. Human speech is an extreme version of this …

Speech- and language-linked FOXP2 mutation targets protein motors in striatal neurons

HY Kuo, SY Chen, RC Huang, H Takahashi, YH Lee… - Brain, 2023 - academic.oup.com
Human speech and language are among the most complex motor and cognitive abilities.
The discovery of a mutation in the transcription factor FOXP2 in KE family members with …

Foxp1 regulation of neonatal vocalizations via cortical development

N Usui, DJ Araujo, A Kulkarni, J Ellegood… - Genes & …, 2017 - genesdev.cshlp.org
The molecular mechanisms driving brain development at risk in autism spectrum disorders
(ASDs) remain mostly unknown. Previous studies have implicated the transcription factor …