Toxoplasma gondii and Plasmodium falciparum are important human pathogens. These
parasites and many of their apicomplexan relatives undergo a complex developmental …

The malaria parasite, Plasmodium falciparum, harbours a relict plastid known as the
'apicoplast'. The discovery of the apicoplast ushered in an exciting new prospect for drug …

Apicomplexan parasites exhibit tremendous diversity in much of their fundamental cell
biology, but study of these organisms using light microscopy is often hindered by their small …

Intracellular malaria parasites require lipids for growth and replication. They possess a
prokaryotic type II fatty acid synthesis (FAS II) pathway that localizes to the apicoplast plastid …

Malaria remains a significant threat to global health, and despite concerted efforts to curb the
disease, malaria-related morbidity and mortality increased in recent years. Malaria is caused …

Abstract Background The apicomplexan parasite Plasmodium falciparum causes the most
severe form of malaria in humans. After invasion into erythrocytes, asexual parasite stages …

Babesia bovis is an apicomplexan tick-transmitted pathogen of cattle imposing a global risk
and severe constraints to livestock health and economic development. The complete …

Apicomplexan parasites constitute one of the most significant groups of pathogens infecting
humans and animals. The liver stage sporozoites of Plasmodium spp. and tachyzoites of …

Tetracyclines are effective but slow-acting antimalarial drugs whose mechanism of action
remains uncertain. To characterize the antimalarial mechanism of tetracyclines, we …

Malaria is caused by intraerythrocytic protozoan parasites belonging to Plasmodium
spp.(phylum Apicomplexa) that produce significant morbidity and mortality, mostly in …