Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …

Neuroinflammation play an important role in Alzheimer's disease pathogenesis. Advances in
molecular imaging using positron emission tomography have provided insights into the time …

Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …

Metallic radionuclides possess a variety of half-lives, emission types, energies, and
branching ratios, making it possible to apply them as diagnostic and/or therapeutic agents …

Background and Purpose Diacetyl‐bis (4‐methyl‐3‐thiosemicarbazonato) copperII (CuII
(atsm)) ameliorates neurodegeneration and delays disease progression in mouse models of …

Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that causes
degeneration of the lower and upper motor neurons and is the most prevalent motor neuron …

Quantitative susceptibility mapping (QSM) has been used to study susceptibility changes
that may occur based on tissue composition and mineral deposition. Iron is a primary …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by
the loss of motor neurons in the brain and spinal cord. While the exact causes of ALS are still …

The world population is aging rapidly, and increasing lifespan exacerbates the burden of
age-related health issues. On the other hand, premature aging has begun to be a problem …