Advances in microfluidics: technical innovations and applications in diagnostics and therapeutics

G Aubry, HJ Lee, H Lu - Analytical Chemistry, 2023 - ACS Publications
Microfluidics describes the study of systems that operate fluids at miniature scales, often in
microchannels. It is powerful in scaling down biological experiments by many orders of …

Electroactive 4D Porous Scaffold Based on Conducting Polymer as a Responsive and Dynamic In Vitro Cell Culture Platform

F Hahn, A Ferrandez-Montero, M Queri… - … Applied Materials & …, 2024 - ACS Publications
In vivo, cells reside in a 3D porous and dynamic microenvironment. It provides biochemical
and biophysical cues that regulate cell behavior in physiological and pathological …

Mechanically programming anisotropy in engineered muscle with actuating extracellular matrices

B Rios, A Bu, T Sheehan, H Kobeissi, S Kohli, K Shah… - Device, 2023 - cell.com
The hierarchical design and adaptive functionalities of biological tissues are driven by
dynamic biochemical, electrical, and mechanical signaling between cells and their …

Structure formation of PNIPAM microgels in foams and foam films

M Kühnhammer, K Gräff, E Loran, O Soltwedel… - Soft matter, 2022 - pubs.rsc.org
Responsive aqueous foams are very interesting from a fundamental point of view and for
various applications like foam flooding or foam flotation. In this study thermoresponsive …

A Laser‐Driven Microrobot for Thermal Stimulation of Single Cells

P Harder, N İyisan, C Wang, F Kohler… - Advanced …, 2023 - Wiley Online Library
Here, the study presents a thermally activated cell‐signal imaging (TACSI) microrobot,
capable of photothermal actuation, sensing, and light‐driven locomotion. The plasmonic soft …

Magnetically Actuated Hydrogel Stamping-Assisted Cellular Mechanical Analyzer for Stored Blood Quality Detection

L Yu, L Chen, Y Liu, J Zhu, F Wang, L Ma, K Yi… - ACS …, 2023 - ACS Publications
Cellular mechanical property analysis reflecting the physiological and pathological states of
cells plays a crucial role in assessing the quality of stored blood. However, its complex …

Tuning porosity of macroporous hydrogels enables rapid rates of stress relaxation and promotes cell expansion and migration

BA Nerger, K Kashyap, BT Deveney, J Lou… - Proceedings of the …, 2024 - pnas.org
Extracellular matrix (ECM) viscoelasticity broadly regulates cell behavior. While hydrogels
can approximate the viscoelasticity of native ECM, it remains challenging to recapitulate the …

High‐Throughput Single‐Cell Analysis of Local Nascent Protein Deposition in 3D Microenvironments via Extracellular Protein Identification Cytometry (EPIC)

M Meteling, C Johnbosco, A Wolfel… - Advanced …, 2024 - Wiley Online Library
Extracellular matrix (ECM) guides cell behavior and tissue fate. Cell populations are
notoriously heterogeneous leading to large variations in cell behavior at the single‐cell …

[HTML][HTML] A Multi-Functional 3D-Printable Gel-in-Gel System for the Delivery of Probiotics to the Intestine

D Fan, S Diller, S Mansi, C Wang, P Mela, B Özkale… - Food …, 2024 - Elsevier
Bacterial encapsulation has been successfully utilized to either protect probiotics from the
harsh gastrointestinal (GI) environment or to provide them with mucoadhesive properties …

A multiscale approach to assess thermomechanical performance and force generation in nanorobotic microgels

C Wang, P Harder, N İyisan, B Li, L Hiendlmeier… - Nanoscale, 2024 - pubs.rsc.org
We present a multiscale approach to characterize the performance of photothermally
powered, nanorobotic 3D microgels. Optically triggered nanoactuators, consisting of a gold …