[HTML][HTML] Inflammation as a central mechanism in Alzheimer's disease
JW Kinney, SM Bemiller, AS Murtishaw… - Alzheimer's & Dementia …, 2018 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized
by cognitive decline and the presence of two core pathologies, amyloid β plaques and …
by cognitive decline and the presence of two core pathologies, amyloid β plaques and …
[HTML][HTML] Neuroinflammation in Huntington's disease: a starring role for astrocyte and microglia
J Saba, FL Couselo, J Bruno, L Carniglia… - Current …, 2022 - ncbi.nlm.nih.gov
Huntington's disease (HD) is a neurodegenerative genetic disorder caused by a CAG repeat
expansion in the huntingtin gene. HD causes motor, cognitive, and behavioral dysfunction …
expansion in the huntingtin gene. HD causes motor, cognitive, and behavioral dysfunction …
Inflammation in Huntington's disease: A few new twists on an old tale
PAC Valadão, KBS Santos, THF e Vieira… - Journal of …, 2020 - Elsevier
Huntington's disease (HD) is a neurodegenerative disease characterized by prominent loss
of neurons in the striatum and cortex. Traditionally research in HD has focused on brain …
of neurons in the striatum and cortex. Traditionally research in HD has focused on brain …
The microbiota–gut–brain axis in Huntington's disease: pathogenic mechanisms and therapeutic targets
Huntington's disease (HD) is a currently incurable neurogenerative disorder and is typically
characterized by progressive movement disorder (including chorea), cognitive deficits …
characterized by progressive movement disorder (including chorea), cognitive deficits …
Circulating levels of inflammatory biomarkers in Huntington's disease: A systematic review and meta-analysis
Background Huntington's disease (HD) is an autosomal dominant disease caused by an
abnormally high number of CAG repeats at the huntingtin-encoding gene, HTT. This genetic …
abnormally high number of CAG repeats at the huntingtin-encoding gene, HTT. This genetic …
[HTML][HTML] Myelin breakdown in human Huntington's disease: Multi-modal evidence from diffusion MRI and quantitative magnetization transfer
Huntington's disease (HD) leads to white matter (WM) degeneration that may be due to an
early breakdown in axon myelination but in vivo imaging correlates of demyelination remain …
early breakdown in axon myelination but in vivo imaging correlates of demyelination remain …
Fluid and imaging biomarkers for Huntington's disease
Huntington's disease is a chronic progressive neurodegenerative condition for which there
is no disease-modifying treatment. The known genetic cause of Huntington's disease makes …
is no disease-modifying treatment. The known genetic cause of Huntington's disease makes …
Translating cell therapies for neurodegenerative diseases: Huntington's disease as a model disorder
AE Rosser, ME Busse, WP Gray, RA Badin, AL Perrier… - Brain, 2022 - academic.oup.com
There has been substantial progress in the development of regenerative medicine strategies
for CNS disorders over the last decade, with progression to early clinical studies for some …
for CNS disorders over the last decade, with progression to early clinical studies for some …
Selected CSF biomarkers indicate no evidence of early neuroinflammation in Huntington disease
T Vinther-Jensen, L Börnsen… - Neurology …, 2016 - AAN Enterprises
Objective: To investigate CSF biomarkers of neuroinflammation and neurodegeneration in
Huntington disease (HD) gene-expansion carriers compared to controls and to investigate …
Huntington disease (HD) gene-expansion carriers compared to controls and to investigate …
The updated development of blood-based biomarkers for Huntington's disease
S Zhang, Y Cheng, H Shang - Journal of Neurology, 2023 - Springer
Huntington's disease is a progressive neurodegenerative disease caused by mutation of the
huntingtin (HTT) gene. The identification of mutation carriers before symptom onset provides …
huntingtin (HTT) gene. The identification of mutation carriers before symptom onset provides …