Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized
by cognitive decline and the presence of two core pathologies, amyloid β plaques and …

Huntington's disease (HD) is a neurodegenerative genetic disorder caused by a CAG repeat
expansion in the huntingtin gene. HD causes motor, cognitive, and behavioral dysfunction …

Huntington's disease (HD) is a neurodegenerative disease characterized by prominent loss
of neurons in the striatum and cortex. Traditionally research in HD has focused on brain …

Huntington's disease (HD) is a currently incurable neurogenerative disorder and is typically
characterized by progressive movement disorder (including chorea), cognitive deficits …

Background Huntington's disease (HD) is an autosomal dominant disease caused by an
abnormally high number of CAG repeats at the huntingtin-encoding gene, HTT. This genetic …

Huntington's disease (HD) leads to white matter (WM) degeneration that may be due to an
early breakdown in axon myelination but in vivo imaging correlates of demyelination remain …

Huntington's disease is a chronic progressive neurodegenerative condition for which there
is no disease-modifying treatment. The known genetic cause of Huntington's disease makes …

There has been substantial progress in the development of regenerative medicine strategies
for CNS disorders over the last decade, with progression to early clinical studies for some …

Objective: To investigate CSF biomarkers of neuroinflammation and neurodegeneration in
Huntington disease (HD) gene-expansion carriers compared to controls and to investigate …

Huntington's disease is a progressive neurodegenerative disease caused by mutation of the
huntingtin (HTT) gene. The identification of mutation carriers before symptom onset provides …