[HTML][HTML] Emerging peptide antibiotics with therapeutic potential

G Upert, A Luther, D Obrecht, P Ermert - Medicine in drug discovery, 2021 - Elsevier
This review covers some of the recent progress in the field of peptide antibiotics with a focus
on compounds with novel or established mode of action and with demonstrated efficacy in …

Optical biosensors for therapeutic drug monitoring

V Garzón, DG Pinacho, RH Bustos, G Garzón… - Biosensors, 2019 - mdpi.com
Therapeutic drug monitoring (TDM) is a fundamental tool when administering drugs that
have a limited dosage or high toxicity, which could endanger the lives of patients. To carry …

Tissue penetration of antimicrobials in intensive care unit patients: a systematic review—part I

S Finazzi, G Luci, C Olivieri, M Langer, G Mandelli… - Antibiotics, 2022 - mdpi.com
The challenging severity of some infections, especially in critically ill patients, makes the
diffusion of antimicrobial drugs within tissues one of the cornerstones of chemotherapy. The …

Challenges of colistin use in ICU and therapeutic drug monitoring: A literature review

J Rychlíčková, V Kubíčková, P Suk, K Urbánek - Antibiotics, 2023 - mdpi.com
The emerging resistance of Gram-negative bacteria is a growing problem worldwide.
Together with the financial cost, limited efficacy, and local unavailability of newer antibiotics …

Antimicrobial and Anti-Biofilm Activity of Polymyxin E Alone and in Combination with Probiotic Strains of Bacillus subtilis KATMIRA1933 and Bacillus amyloliquefaciens B-1895 …

M Al-Dulaimi, A Algburi, A Abdelhameed, MS Mazanko… - Pathogens, 2021 - mdpi.com
Acinetobacter spp., the nosocomial pathogen, forms strong biofilms and is resistant to
numerous antibiotics, causing persistent infections. This study investigates the antibacterial …

Mechanism and potential risk of antibiotic resistant bacteria carrying last resort antibiotic resistance genes under electrochemical treatment

LX Meng, YJ Sun, L Zhu, ZJ Lin, XY Shuai… - Science of The Total …, 2022 - Elsevier
The significant rise in the number of antibiotic resistance genes (ARGs) that resulted from
our abuse of antibiotics could do severe harm to public health as well as to the environment …

Combining colistin and fluconazole synergistically increases fungal membrane permeability and antifungal cidality

M Bibi, S Murphy, RI Benhamou… - ACS Infectious …, 2021 - ACS Publications
The increasing emergence of drug-resistant fungal pathogens, together with the limited
number of available antifungal drugs, presents serious clinical challenges to treating …

Some suggestions from PK/PD principles to contain resistance in the clinical setting—focus on ICU patients and gram-negative strains

C Adembri, A Novelli, S Nobili - Antibiotics, 2020 - mdpi.com
The containment of the phenomenon of resistance towards antimicrobials is a priority,
especially in preserving molecules acting against Gram-negative pathogens, which …

Synthesis, Characterization, and Bactericidal Activity of a 4-Ammoniumbuthylstyrene-Based Random Copolymer

S Alfei, G Piatti, D Caviglia, AM Schito - Polymers, 2021 - mdpi.com
The growing resistance of bacteria to current chemotherapy is a global concern that urgently
requires new and effective antimicrobial agents, aimed at curing untreatable infection …

[HTML][HTML] Antimicrobial Resistance of Staphylococcus spp. from Human Specimens Submitted to Diagnostic Laboratories in South Africa, 2012–2017

TT Sigudu, JW Oguttu, DN Qekwana - Microorganisms, 2024 - mdpi.com
Antimicrobial resistance (AMR) poses a significant worldwide health challenge associated
with prolonged illnesses, increased healthcare costs, and high mortality rates. The present …