Mechanism of natural antioxidants regulating advanced glycosylation end products of Maillard reaction

W Jia, A Guo, R Zhang, L Shi - Food Chemistry, 2023 - Elsevier
According to the investigation of Food and Drug Administration 2021, one hundred and
twenty-six potentially harmful substances are produced by Maillard reaction. Discovery of …

RAGE inhibitors in neurodegenerative diseases

VP Reddy, P Aryal, P Soni - Biomedicines, 2023 - mdpi.com
Nonenzymatic reactions of reducing sugars with primary amino groups of amino acids,
proteins, and nucleic acids, followed by oxidative degradations would lead to the formation …

Food polyphenols as preventive medicine

J Kanner - Antioxidants, 2023 - mdpi.com
Reactive oxygen species (ROS) are the initiators in foods and in the stomach of oxidized
dietary lipids, proteins, and lipid-oxidation end-products (ALEs), inducing in humans the …

Communal interaction of glycation and gut microbes in diabetes mellitus, Alzheimer's disease, and Parkinson's disease pathogenesis

RS Patil, RS Tupe - Medicinal Research Reviews, 2024 - Wiley Online Library
Diabetes and its complications, Alzheimer's disease (AD), and Parkinson's disease (PD) are
increasing gradually, reflecting a global threat vis‐à‐vis expressing the essentiality of a …

Simultaneous regulation of AGE/RAGE signaling and MMP-9 expression by an immunomodulating hydrogel accelerates healing in diabetic wounds

A Banerjee, P Singh, PA Sheikh, A Kumar, V Koul… - Biomaterials …, 2024 - Elsevier
Purpose In chronic hyperglycemia, the advanced glycation end product (AGE) interacts with
its receptor (RAGE) and contributes to impaired wound healing by inducing oxidative stress …

Human iPSC-based disease modeling studies identify a common mechanistic defect and potential therapies for AMD and related macular dystrophies

S Dalvi, M Roll, A Chatterjee, LK Kumar, A Bhogavalli… - Developmental Cell, 2024 - cell.com
Age-related macular degeneration (AMD) and related macular dystrophies (MDs) primarily
affect the retinal pigment epithelium (RPE) in the eye. A hallmark of AMD/MDs that drives …

Impact of western diet and ultra-processed food on the intestinal mucus barrier

C Stolfi, T Pacifico, G Monteleone, F Laudisi - Biomedicines, 2023 - mdpi.com
The intestinal epithelial barrier plays a key role in the absorption of nutrients and water, in
the regulation of the interactions between luminal contents and the underlying immune cells …

Long COVID and the neuroendocrinology of microbial translocation outside the GI tract: some treatment strategies

A Sfera, C Osorio, S Hazan, Z Kozlakidis… - Endocrines, 2022 - mdpi.com
Similar to previous pandemics, COVID-19 has been succeeded by well-documented post-
infectious sequelae, including chronic fatigue, cough, shortness of breath, myalgia, and …

A Gently Processed Skim Milk‐Derived Whey Protein Concentrate for Infant Formula: Effects on Gut Development and Immunity in Preterm Pigs

K Aasmul‐Olsen, HG Akıllıoğlu… - Molecular Nutrition & …, 2024 - Wiley Online Library
Scope Processing of whey protein concentrate (WPC) for infant formulas may induce protein
modifications with severe consequences for preterm newborn development. The study …

Causal linkage between type 2 diabetes mellitus and inflammatory bowel disease: an integrated Mendelian randomization study and bioinformatics analysis

X Xiao, X Wu, L Yi, F You, X Li, C Xiao - Frontiers in Endocrinology, 2024 - frontiersin.org
Background Observational studies have indicated associations between type 2 diabetes
mellitus (T2DM) and both colorectal cancer (CRC) and inflammatory bowel disease (IBD) …