Some natural photosensitizers and their medicinal properties for use in photodynamic therapy

TP Kubrak, P Kołodziej, J Sawicki, A Mazur… - Molecules, 2022 - mdpi.com
Despite significant advances in early diagnosis and treatment, cancer is one of the leading
causes of death. Photodynamic therapy (PDT) is a therapy for the treatment of many …

Riboflavin and health: A review of recent human research

K Thakur, SK Tomar, AK Singh, S Mandal… - Critical reviews in food …, 2017 - Taylor & Francis
There has lately been a renewed interest in Riboflavin owing to insight into its recognition as
an essential component of cellular biochemistry. The knowledge of the mechanisms and …

Biosynthesized Silver Nanoparticle (AgNP) From Pandanus odorifer Leaf Extract Exhibits Anti-metastasis and Anti-biofilm Potentials

A Hussain, MF Alajmi, MA Khan, SA Pervez… - Frontiers in …, 2019 - frontiersin.org
Cancer and the associated secondary bacterial infections are leading cause of mortality,
due to the paucity of effective drugs. Here, we have synthesized silver nanoparticles …

Medicinal benefits, biological and nanoencapsulation functions of riboflavin with its toxicity profile-A narrative review

TY Lee, N Farah, VK Chin, CW Lim, PP Chong… - Nutrition Research, 2023 - Elsevier
Riboflavin is a precursor of the essential coenzymes flavin mononucleotide (FMN) and flavin
adenine dinucleotide (FAD). Both possess antioxidant properties and are involved in …

Ameliorative effects of rutin against cisplatin-induced reproductive toxicity in male rats

S Jahan, A Munawar, S Razak, S Anam, QU Ain… - BMC urology, 2018 - Springer
Background Cisplatin (CP) or cis-diammine dichloroplatinum (II) is a platinum based
standard antineoplastic drug which is used against variety of solid tumors and neoplasms …

Ameliorative effect of riboflavin on hyperglycemia, oxidative stress and DNA damage in type-2 diabetic mice: Mechanistic and therapeutic strategies

MM Alam, S Iqbal, I Naseem - Archives of Biochemistry and Biophysics, 2015 - Elsevier
Increasing evidence in both experimental and clinical studies suggests that oxidative stress
play a major role in the pathogenesis of type-2 diabetes mellitus (T2DM). Abnormally high …

Nephroprotective activities of rosmarinic acid against cisplatin-induced kidney injury in mice

R Domitrović, I Potočnjak, Ž Crnčević-Orlić… - Food and Chemical …, 2014 - Elsevier
Rosmarinic acid (RA) is a natural phenolic compound with a broad range of applications,
from food preservatives to cosmetics. Increasing amounts of evidence suggests its beneficial …

Discovery and development of natural products and their derivatives as photosensitizers for photodynamic therapy

Q Xiao, J Wu, X Pang, Y Jiang, P Wang… - Current Medicinal …, 2018 - ingentaconnect.com
Photodynamic therapy (PDT) has been developed as an alternative modality for the
management of neoplastic and nonneoplastic diseases. It is a minimally invasive treatment …

Disrupting protein NEDDylation with MLN4924 is a novel strategy to target cisplatin resistance in ovarian cancer

ST Nawrocki, KR Kelly, PG Smith, CM Espitia… - Clinical cancer …, 2013 - AACR
Purpose: Ovarian cancer has the highest mortality rate of all female reproductive
malignancies. Drug resistance is a major cause of treatment failure and novel therapeutic …

Alleviation of hepatic injury by chrysin in cisplatin administered rats: probable role of oxidative and inflammatory markers

MU Rehman, N Ali, S Rashid, T Jain, S Nafees… - Pharmacological …, 2014 - Elsevier
Background Cisplatin is an effective and extensively used chemotherapeutic agent to treat
range of malignancies, but its therapeutic use is limited because of dose-dependent …