A projected doubling in the global population of people aged≥ 60 y by the year 2050 has
major health and economic implications, especially in developing regions. Burdens of …

Declines in skeletal muscle mass and strength are major contributors to increased mortality,
morbidity and reduced quality of life in older people. Recommended Dietary …

Sarcopenia, the age-associated loss of skeletal muscle mass and function, has considerable
societal consequences for the development of frailty, disability, and health care planning. A …

Background. Protein is a macronutrient essential for growth, muscle function, immunity and
overall tissue homeostasis. Suboptimal protein intake can significantly impact physical …

Obesity causes serious medical complications and impairs quality of life. Moreover, in older
persons, obesity can exacerbate the age-related decline in physical function and lead to …

Frailty is a geriatric syndrome that refers to a state of reduced resiliency to stressful events
that occurs in response to physiological and/or psychosocial detriments. Frailty is a predictor …

Background Evidence for the effectiveness of nutritional supplements containing protein and
energy, often prescribed for older people, is limited. Malnutrition is more common in this age …

A wealth of observational studies show that low testosterone is associated with insulin
resistance and with an increased risk of diabetes and the metabolic syndrome. Experimental …

The human microbiome contains a vast array of microbes and genes that show greater
complexity than the host's own karyome; the functions of many of these microbes are …

Sarcopenia is likely a multifactorial condition that impairs physical function and predisposes
to disability. It may be prevented or treated with lifestyle interventions and pharmacological …