The NLRP3 inflammasome in neurodegenerative disorders: insights from epileptic models
L Palumbo, M Carinci, A Guarino, L Asth, S Zucchini… - Biomedicines, 2023 - mdpi.com
Neuroinflammation represents a dynamic process of defense and protection against the
harmful action of infectious agents or other detrimental stimuli in the central nervous system …
harmful action of infectious agents or other detrimental stimuli in the central nervous system …
Neuroprotective potential of biochanin-A and review of the molecular mechanisms involved
Biochanin-A is a naturally occurring plant phytoestrogen, which mimics specific the agonistic
activity of estrogens. Biochanin-A is known to possess numerous activities, including …
activity of estrogens. Biochanin-A is known to possess numerous activities, including …
An explanation of the role of pyroptosis playing in epilepsy
X Zhang, T Zhao, S Su, L Li, Y Zhang, J Yan… - International …, 2024 - Elsevier
Epilepsy is a severe central nervous system disorder characterized by an imbalance
between neuronal excitation and inhibition, resulting in heightened neuronal excitability …
between neuronal excitation and inhibition, resulting in heightened neuronal excitability …
[HTML][HTML] Biochanin A inhibits cardiac hypertrophy and fibrosis in vivo and in vitro
Z Feng, N Zhang, J Bai, Q Lin, Y Xie, Y Xia - Biomedicine & …, 2024 - Elsevier
The heart undergoes pathological cardiac hypertrophy as an adaptive response to
prolonged pathological stimulation, leading to cardiomyocyte hypertrophy, fibroblast …
prolonged pathological stimulation, leading to cardiomyocyte hypertrophy, fibroblast …
Mechanism of NLRP3 inflammasome in epilepsy and related therapeutic agents
J Chen, Y Gao, N Liu, D Hai, W Wei, Y Liu, X Lan, X Jin… - Neuroscience, 2024 - Elsevier
Epilepsy is one of the most widespread and complex diseases in the central nervous system
(CNS), affecting approximately 65 million people globally, an important factor resulting in …
(CNS), affecting approximately 65 million people globally, an important factor resulting in …
Biochanin a ameliorates DSS-induced ulcerative colitis by improving colonic barrier function and protects against the development of spontaneous colitis in the Muc2 …
H Zhang, X Wang, L Zhao, K Zhang, J Cui… - Chemico-Biological …, 2024 - Elsevier
There is an increasing appreciation that colonic barrier function is closely related to the
development and progression of colitis. The mucus layer is a crucial component of the …
development and progression of colitis. The mucus layer is a crucial component of the …
Metabolomic Profiling and In Vivo Antiepileptic Effect of Zygophyllum album Aerial Parts and Roots Crude Extracts against Pentylenetetrazole-Induced Kindling in …
The chemical profiles of both Zygophyllum album (Z. album) aerial parts and roots extracts
were evaluated with LC-ESI-TOF-MS/MS analysis. Twenty-four compounds were detected …
were evaluated with LC-ESI-TOF-MS/MS analysis. Twenty-four compounds were detected …
Computational and Experimental Approaches Exploring the Role of Hesperetin in Improving Autophagy in Rat Diabetic Retinopathy
Diabetic retinopathy (DR) is a debilitating diabetic disorder of the retinal microvasculature
and the main cause of avoidable blindness in old people. Hesperetin is a plant flavanone …
and the main cause of avoidable blindness in old people. Hesperetin is a plant flavanone …
Quetiapine attenuates cadmium neurotoxicity by suppressing oxidative stress, inflammation, and pyroptosis
Abstract Background Cadmium (Cd) is a heavy metal with extremely harmful toxic effects on
the brain. Quetiapine (QTP) has unique neuroprotective effects with anti-inflammatory and …
the brain. Quetiapine (QTP) has unique neuroprotective effects with anti-inflammatory and …
Harnessing Therapeutic Potentials of Biochanin A in Neurological Disorders: Pharmacokinetic and Pharmacodynamic Overview
A Kumar, E Angelopoulou, ES Pyrgelis… - Chemistry & …, 2024 - Wiley Online Library
Biochanin A, an isoflavone flavonoid with estrogenic activity, is naturally found in red clover
and other legumes. It possesses a wide range of pharmacological properties, including …
and other legumes. It possesses a wide range of pharmacological properties, including …