The biosynthesis of bacterial cell wall peptidoglycan is a complex process that involves
enzyme reactions that take place in the cytoplasm (synthesis of the nucleotide precursors) …

2.2 Phosphoglucosamine mutase 2.3 GlmU synthase 3 Formation of UDP-N-acetylmuramic
acid 3.1 Transferase MurA 3.2 MurB reductase 4 Formation of UDP-MurNAc-peptides 4.1 …

Staphylococcus aureus Mu50, which has reduced susceptibility to vancomycin, has a
remarkably thickened cell wall with an increased proportion of glutamine nonamidated …

l-Glutamine: d-fructose-6-phosphate amidotransferase, known under trivial name of
glucosamine-6-phosphate synthase, as the only member of the amidotransferase subfamily …

Glutamine-dependent amidotransferases have been known for more than 30 years. The
mechanism by which these enzymes generate ammonia from the glutamine amide nitrogen …

Abstract d‐Glucosamine is an important building block of major structural components of the
fungal cell wall, namely chitin, chitosan and mannoproteins. Other amino sugars, such as d …

The cell wall (CW) of fungi exhibits a complex structure and a characteristic chemical
composition consisting almost entirely of interacting crystalline and amorphous …

l-Glutamine: d-fructose-6-phosphate amidotransferase, also known as glucosamine-6-
phosphate synthase (GlcN6P synthase), which catalyzes the first step in a pathway leading …

Glucosamine‐6‐P occupies a central position between cell wall synthesis and glycolysis. In
the initial steps leading to peptidoglycan precursor formation glucosamine‐6‐P is processed …

The range of antibiotic therapy for the control of bacterial infections is becoming increasingly
limited because of the rapid rise in multidrug resistance in clinical bacterial isolates. A few …