[HTML][HTML] Current trends and challenges in cancer management and therapy using designer nanomaterials

PN Navya, A Kaphle, SP Srinivas, SK Bhargava… - Nano convergence, 2019 - Springer
Nanotechnology has the potential to circumvent several drawbacks of conventional
therapeutic formulations. In fact, significant strides have been made towards the application …

[HTML][HTML] Recent advances in drug delivery systems for targeting cancer stem cells

H Duan, Y Liu, Z Gao, W Huang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …

Liposome-based drug co-delivery systems in cancer cells

SZ Vahed, R Salehi, S Davaran, S Sharifi - Materials Science and …, 2017 - Elsevier
Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

Salinomycin as a potent anticancer stem cell agent: State of the art and future directions

D Qi, Y Liu, J Li, JH Huang, X Hu… - Medicinal research …, 2022 - Wiley Online Library
Cancer stem cells (CSCs) are a small subpopulation of cells within a tumor that can both self‐
renew and differentiate into other cell types forming the heterogeneous tumor bulk. Since …

CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel

E Muntimadugu, R Kumar, S Saladi, TA Rafeeqi… - Colloids and Surfaces B …, 2016 - Elsevier
This combinational therapy is mainly aimed for complete eradication of tumor by killing both
cancer cells and cancer stem cells. Salinomycin (SLM) was targeted towards cancer stem …

Cancer stem cells-emanated therapy resistance: implications for liposomal drug delivery systems

H Dianat-Moghadam, M Heidarifard… - Journal of controlled …, 2018 - Elsevier
It is verified that failure in cancer therapy by conventional chemotherapeutic agents arise
from cancer heterogeneity. That, a small subpopulation of cancer cells known as “cancer …

[HTML][HTML] Targeting cancer stem cells as the key driver of carcinogenesis and therapeutic resistance

RA Eid, M Alaa Edeen, EM Shedid, ASS Kamal… - International Journal of …, 2023 - mdpi.com
The emerging concept of cancer stem cells (CSCs) as the key driver behind carcinogenesis,
progression, and diversity has displaced the prior model of a tumor composed of cells with …

CAR-T cells surface-engineered with drug-encapsulated nanoparticles can ameliorate intratumoral T-cell hypofunction

N Siriwon, YJ Kim, E Siegler, X Chen, JA Rohrs… - Cancer immunology …, 2018 - AACR
One limiting factor of CAR T-cell therapy for treatment of solid cancers is the suppressive
tumor microenvironment (TME), which inactivates the function of tumor-infiltrating …

[HTML][HTML] Cabazitaxel and silibinin co-encapsulated cationic liposomes for CD44 targeted delivery: a new insight into nanomedicine based combinational …

S Mahira, N Kommineni, GM Husain, W Khan - Biomedicine & …, 2019 - Elsevier
Cancer stem cells (CSCs) are the promising targets for cancer chemotherapy that cannot be
eliminated by conventional chemotherapy. In this study cationic liposomes of cabazitaxel …

Co-delivery of docetaxel and salinomycin to target both breast cancer cells and stem cells by PLGA/TPGS nanoparticles

J Gao, J Liu, F Xie, Y Lu, C Yin… - International journal of …, 2019 - Taylor & Francis
Purpose Conventional chemotherapy is hampered by the presence of breast cancer stem
cells (BCSCs). It is crucial to eradicating both the bulky breast cancer cells and BCSCs …