[HTML][HTML] Current trends and challenges in cancer management and therapy using designer nanomaterials
Nanotechnology has the potential to circumvent several drawbacks of conventional
therapeutic formulations. In fact, significant strides have been made towards the application …
therapeutic formulations. In fact, significant strides have been made towards the application …
[HTML][HTML] Recent advances in drug delivery systems for targeting cancer stem cells
H Duan, Y Liu, Z Gao, W Huang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …
Liposome-based drug co-delivery systems in cancer cells
Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …
Salinomycin as a potent anticancer stem cell agent: State of the art and future directions
D Qi, Y Liu, J Li, JH Huang, X Hu… - Medicinal research …, 2022 - Wiley Online Library
Cancer stem cells (CSCs) are a small subpopulation of cells within a tumor that can both self‐
renew and differentiate into other cell types forming the heterogeneous tumor bulk. Since …
renew and differentiate into other cell types forming the heterogeneous tumor bulk. Since …
CD44 targeted chemotherapy for co-eradication of breast cancer stem cells and cancer cells using polymeric nanoparticles of salinomycin and paclitaxel
E Muntimadugu, R Kumar, S Saladi, TA Rafeeqi… - Colloids and Surfaces B …, 2016 - Elsevier
This combinational therapy is mainly aimed for complete eradication of tumor by killing both
cancer cells and cancer stem cells. Salinomycin (SLM) was targeted towards cancer stem …
cancer cells and cancer stem cells. Salinomycin (SLM) was targeted towards cancer stem …
Cancer stem cells-emanated therapy resistance: implications for liposomal drug delivery systems
H Dianat-Moghadam, M Heidarifard… - Journal of controlled …, 2018 - Elsevier
It is verified that failure in cancer therapy by conventional chemotherapeutic agents arise
from cancer heterogeneity. That, a small subpopulation of cancer cells known as “cancer …
from cancer heterogeneity. That, a small subpopulation of cancer cells known as “cancer …
[HTML][HTML] Targeting cancer stem cells as the key driver of carcinogenesis and therapeutic resistance
The emerging concept of cancer stem cells (CSCs) as the key driver behind carcinogenesis,
progression, and diversity has displaced the prior model of a tumor composed of cells with …
progression, and diversity has displaced the prior model of a tumor composed of cells with …
CAR-T cells surface-engineered with drug-encapsulated nanoparticles can ameliorate intratumoral T-cell hypofunction
One limiting factor of CAR T-cell therapy for treatment of solid cancers is the suppressive
tumor microenvironment (TME), which inactivates the function of tumor-infiltrating …
tumor microenvironment (TME), which inactivates the function of tumor-infiltrating …
[HTML][HTML] Cabazitaxel and silibinin co-encapsulated cationic liposomes for CD44 targeted delivery: a new insight into nanomedicine based combinational …
Cancer stem cells (CSCs) are the promising targets for cancer chemotherapy that cannot be
eliminated by conventional chemotherapy. In this study cationic liposomes of cabazitaxel …
eliminated by conventional chemotherapy. In this study cationic liposomes of cabazitaxel …
Co-delivery of docetaxel and salinomycin to target both breast cancer cells and stem cells by PLGA/TPGS nanoparticles
Purpose Conventional chemotherapy is hampered by the presence of breast cancer stem
cells (BCSCs). It is crucial to eradicating both the bulky breast cancer cells and BCSCs …
cells (BCSCs). It is crucial to eradicating both the bulky breast cancer cells and BCSCs …