Application of Box-Behnken experimental design and response surface methodology for selecting the optimum RP-HPLC conditions for the simultaneous …

EF Elkady, MA Fouad, AN Mozayad - BMC chemistry, 2022 - Springer
An isocratic RP-HPLC method has been developed for the separation and determination of
methocarbamol (MTL), indomethacin (IND), and betamethasone (BET) in combined dosage …

[图书][B] Thin layer chromatography in drug analysis

L Komsta, M Waksmundzka-Hajnos, J Sherma - 2013 - books.google.com
Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin
layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It …

Poly (vinylidene fluoride-trifluoroethylene)/NAY zeolite hybrid membranes as a drug release platform applied to ibuprofen release

H Salazar, AC Lima, AC Lopes, G Botelho… - Colloids and Surfaces A …, 2015 - Elsevier
Abstract Poly (vinylidene fluoride-trifluoroethylene)/NaY zeolite composite membranes were
prepared by solvent casting and evaluated as a suitable drug release platform through the …

Validated stability indicating RP-HPLC method for determination of paracetamol, methocarbamol and their related substances

EA Abdelaleem, NS Abdelwahab - Analytical Methods, 2013 - pubs.rsc.org
Paracetamol (PAR) and methocarbamol (MET) are co-formulated together in Methorelax®
tablets which are widely used as a muscle relaxant and in the treatment of muscle-skeletal …

Utilizing experimental design and desirability function in optimizing RP-HPLC method for simultaneous determination of some skeletal muscle relaxants and …

AN Mozayad, MA Fouad, EF Elkady - Scientific Reports, 2024 - nature.com
An experimental design and response surface methodologies using Plackett–Burman and
Box-Behnken designs were applied for selecting and optimizing the most appropriate …

Determination of ibuprofen and phenylephrine in tablets by high-performance thin layer chromatography and in plasma by high-performance liquid chromatography …

MAA Ragab, MH Abdel-Hay, HM Ahmed… - Journal of …, 2019 - academic.oup.com
Two chromatographic methods (high performance thin layer chromatography (HPTLC) and
high performance liquid chromatography–diode array detector (HPLC-DAD)), were …

Simultaneous determination of methocarbamol and ibuprofen by first derivative synchronous fluorescence spectroscopic method in their binary mixture and spiked …

NS Abdelwahab, MM Abdelrahman - Journal of fluorescence, 2014 - Springer
Methocarbamol is formulated with Ibuprofen for treatment of alleviated pain associated with
muscle spasm. This manuscript describes a sensitive and selective first derivative …

Manipulating ratio spectra for the spectrophotometric analysis of diclofenac sodium and pantoprazole sodium in laboratory mixtures and tablet formulation

NM Bhatt, VD Chavada, M Sanyal… - The scientific world …, 2014 - Wiley Online Library
Objective. Three sensitive, selective, and precise spectrophotometric methods based on
manipulation of ratio spectra, have been developed and validated for the determination of …

A micellar HPLC method for simultaneous determination of methocarbamol in three different tablets using single run; application to human plasma and evaluation of …

SAEA Mohamed, FF Belal - Microchemical Journal, 2019 - Elsevier
Methocarbamol is a well-known centrally acting skeletal muscle relaxant and is usually
combined with analgesics like paracetamol, diclofenac and ibuprofen for treatment of …

Effective spectrophotometric methods for resolving the superimposed spectra of Diclofenac Potassium and Methocarbamol

SF El-Malla, AA Hamza, SH Elagamy - Spectrochimica Acta Part A …, 2023 - Elsevier
The UV spectra of Diclofenac Potassium DIC and Methocarbamol MET are superimposed
making their analysis using direct or derivative spectrophotometric methods quite …