Advancing tissue decellularized hydrogels for engineering human organoids
The extracellular matrix plays a critical role in bioinstructing cellular self‐assembly and
spatial (re) configuration processes that culminate in human organoids in vitro generation …
spatial (re) configuration processes that culminate in human organoids in vitro generation …
Insights into the use of genetically modified decellularized biomaterials for tissue engineering and regenerative medicine
D Zhu, Z Jiang, N Li, X Wang, L Ren, Y Ye… - Advanced Drug Delivery …, 2022 - Elsevier
Various modifications have been performed on biomaterials to improve their applications in
tissue engineering and regenerative medicine. However, the challenges of immunogenicity …
tissue engineering and regenerative medicine. However, the challenges of immunogenicity …
Spatio-temporal dynamics enhance cellular diversity, neuronal function and further maturation of human cerebral organoids
P Saglam-Metiner, U Devamoglu, Y Filiz… - Communications …, 2023 - nature.com
The bioengineerined and whole matured human brain organoids stand as highly valuable
three-dimensional in vitro brain-mimetic models to recapitulate in vivo brain development …
three-dimensional in vitro brain-mimetic models to recapitulate in vivo brain development …
[HTML][HTML] Rise of tissue-and species-specific 3D bioprinting based on decellularized extracellular matrix-derived bioinks and bioresins
L Elomaa, A Almalla, E Keshi, KH Hillebrandt… - Biomaterials and …, 2023 - Elsevier
Thanks to its natural complexity and functionality, decellularized extracellular matrix (dECM)
serves as an excellent foundation for creating highly cell-compatible bioinks and bioresins …
serves as an excellent foundation for creating highly cell-compatible bioinks and bioresins …
Humanized brain organoids-on-chip integrated with sensors for screening neuronal activity and neurotoxicity
The complex structure and function of the human central nervous system that develops from
the neural tube made in vitro modeling quite challenging until the discovery of brain …
the neural tube made in vitro modeling quite challenging until the discovery of brain …
Characterization of a decellularized pericardium extracellular matrix hydrogel for regenerative medicine: insights on animal-to-animal variability
D Di Francesco, E Marcello, S Casarella… - … in bioengineering and …, 2024 - frontiersin.org
In the past years, the use of hydrogels derived from decellularized extracellular matrix
(dECM) for regenerative medicine purposes has significantly increased. The intrinsic …
(dECM) for regenerative medicine purposes has significantly increased. The intrinsic …
Differentiation of neurons, astrocytes, oligodendrocytes and microglia from human induced pluripotent stem cells to form neural tissue-on-chip: a neuroinflammation …
P Saglam-Metiner, E Duran, L Sabour-Takanlou… - Stem Cell Reviews and …, 2024 - Springer
Advances in stem cell (SC) technology allow the generation of cellular models that
recapitulate the histological, molecular and physiological properties of humanized in vitro …
recapitulate the histological, molecular and physiological properties of humanized in vitro …
Bioinspired microstructures through decellularization of plants for tissue engineering applications
Y Arslan, A Paradiso, N Celiktas, T Erdogan… - European Polymer …, 2023 - Elsevier
In nature, various patterns such as branches, stripes, spirals, and hexagons exist in
biological and natural systems, from nano-to macro-scale. These hierarchical structures …
biological and natural systems, from nano-to macro-scale. These hierarchical structures …
Essential Oil and Supercritical Carbon Dioxide Extract of Grapefruit Peels Formulated for Candida albicans Infections: Evaluation by an in Vitro Model to Study …
B Yaldiz, P Saglam-Metiner, B Cakmak, E Kaya… - ACS …, 2022 - ACS Publications
Resistance to currently available antifungal agents raises the need to develop alternative
remedies. Candida albicans is the most common opportunistic pathogenic fungus of …
remedies. Candida albicans is the most common opportunistic pathogenic fungus of …
Decellularised extracellular matrix-based biomaterials for repair and regeneration of central nervous system
B Yaldiz, P Saglam-Metiner… - Expert Reviews in …, 2021 - cambridge.org
The central nervous system (CNS), consisting of the brain and spinal cord, regulates the
mind and functions of the organs. CNS diseases, leading to changes in neurological …
mind and functions of the organs. CNS diseases, leading to changes in neurological …