Ammonium acetate (NH4Ac) is a widely used solvent additive in native electrospray
ionization (ESI) mass spectrometry. NH4Ac can undergo proton transfer to form ammonia …

Further increase in the acidity in the most denaturing acidic solution is known to induce
compaction of the fully unfolded protein into a compact molten globule. The phenomenon of …

In native mass spectrometry (MS) salts are indispensable for preserving the native structures
of biomolecules, but detrimental to mass sensitivity, resolution, and accuracy. Such a conflict …

Unraveling the mechanism by which native proteins are charged through electrospray
ionization (ESI) has been the focus of considerable research because observable charge …

Streptococcus gordonii is a Gram-positive bacterial species that typically colonizes the
human oral cavity, but can also cause local or systemic diseases. Serine-rich repeat (SRR) …

Electrospray ionization (ESI) mass spectrometry is widely used for interrogating peptides,
proteins, and other biomolecular analytes. A growing number of laboratories use molecular …

Mass spectrometry is routinely used for myriad applications in clinical, industrial, and
research laboratories worldwide. Developments in the areas of ionization sources, high …

The mechanisms whereby protein ions are released from nanodroplets at the liquid–gas
interface have continued to be controversial since electrospray ionization (ESI) mass …

Knotted proteins are fascinating natural biomolecules whose backbones entangle
themselves in a knot. Their particular knotted configurations provide them with a wide range …

Benefitting from the rapid evolution of artificial intelligence and structural biology, an
expanding collection of high-resolution protein structures has greatly improved our …