Oral vaccines are gaining more attention due to their ease of administration, lower
invasiveness, generally greater safety, and lower cost than injectable vaccines. This review …

Extracellular vesicles (EVs)/exosomes are nanosized membrane-bound structures that are
released by virtually all cells. EVs have attracted great attention in the scientific community …

Vaccination with Sabin, a live attenuated oral polio vaccine (OPV), results in robust intestinal
and humoral immunity and has been key to controlling poliomyelitis. As with any RNA virus …

Climate change harms health in all populations. 1 Heatrelated illness and deaths are
increasing worldwide, from heatstroke, adverse pregnancy outcomes, worsened kidney …

Background Type 2 circulating vaccine-derived polioviruses (cVDPV2) from Sabin oral
poliovirus vaccines (OPVs) are the leading cause of poliomyelitis. A novel type 2 OPV …

With the COVID-19 pandemic abating, the only remaining Public Health Emergency of
International Concern is polio [1]. Remarkable progress has been made in reducing the …

Antigen epitope identification is a critical step in the vaccine development process and is a
momentous cornerstone for the development of safe and efficient epitope vaccines. In …

Circulating vaccine-derived poliovirus (cVDPV) outbreaks can occur when oral poliovirus
vaccine strains (most often, Sabin monovalent oral poliovirus vaccine type 2 [mOPV2]) …

Background Despite multiple revisions of targets and timelines in polio eradication plans
since 1988, including changes in supplemental immunization activities (SIAs) that increase …

Threat of resurgence or hope for global eradication of polio... : Current Opinion in Neurology
Threat of resurgence or hope for global eradication of poliovirus? : Current Opinion in …