While there exist some long non-coding RNAs (lncRNAs) that are structurally similar to
mRNAs (capped, spliced, poly a tail), not all of the lncRNAs exhibit these features …

E-cadherin is a transmembrane glycoprotein which connects epithelial cells together at
adherens junctions. In normal cells, E-cadherin exerts its tumour suppressing role mainly by …

Exosomes are nanoscale membrane vesicles secreted from many types of cells. Carrying
functional molecules, exosomes transfer information between cells and mediate many …

MicroRNAs (miRNAs), a highly conserved class of tissue specific, small non-protein coding
RNAs maintain cell homeostasis by negative gene regulation. Proper controlling of miRNA …

Early studies have shown how aberrantly expressed microRNAs are a hallmark of several
diseases like cancer. MicroRNA expression profiling was shown to be associated with …

Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20–23-nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

Tumor suppressor genes (TSGs) are a major type of gatekeeper genes in the cell growth. A
knowledgebase with the systematic collection and curation of TSGs in multiple cancer types …

Mature microRNAs (miRNAs) are single‐stranded RNA molecules of 20–23 nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

We recently proposed that competitive endogenous RNAs (ceRNAs) sequester microRNAs
to regulate mRNA transcripts containing common microRNA recognition elements (MREs) …

For many years cancer research has focused on genetic defects, but during the last decade
epigenetic deregulation has been increasingly recognized as a hallmark of cancer. The …