Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy

A Vezzani, S Balosso, T Ravizza - Nature Reviews Neurology, 2019 - nature.com
Epilepsy is a chronic neurological disease characterized by an enduring propensity for
generation of seizures. The pathogenic processes of seizure generation and recurrence are …

Epilepsy—definition, classification, pathophysiology, and epidemiology

J Falco-Walter - Seminars in neurology, 2020 - thieme-connect.com
Seizures affect the lives of 10% of the global population and result in epilepsy in 1 to 2% of
people around the world. Current knowledge about etiology, diagnosis, and treatments for …

ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology

IE Scheffer, S Berkovic, G Capovilla, MB Connolly… - …, 2017 - Wiley Online Library
Summary The International League Against Epilepsy (ILAE) Classification of the Epilepsies
has been updated to reflect our gain in understanding of the epilepsies and their underlying …

The new definition and classification of seizures and epilepsy

JJ Falco-Walter, IE Scheffer, RS Fisher - Epilepsy research, 2018 - Elsevier
This review discusses the updated classifications of seizures and the epilepsies, which were
recently published by the International League Against Epilepsy (ILAE). While it is always a …

Animal models of seizures and epilepsy: past, present, and future role for the discovery of antiseizure drugs

W Löscher - Neurochemical research, 2017 - Springer
The identification of potential therapeutic agents for the treatment of epilepsy requires the
use of seizure models. Except for some early treatments, including bromides and …

Vagus nerve stimulation in brain diseases: Therapeutic applications and biological mechanisms

Y Wang, G Zhan, Z Cai, B Jiao, Y Zhao, S Li… - … & Biobehavioral Reviews, 2021 - Elsevier
Brain diseases, including neurodegenerative, cerebrovascular and neuropsychiatric
diseases, have posed a deleterious threat to human health and brought a great burden to …

Commonalities in epileptogenic processes from different acute brain insults: Do they translate?

P Klein, R Dingledine, E Aronica, C Bernard… - …, 2018 - Wiley Online Library
The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …

Advances in the development of biomarkers for epilepsy

A Pitkänen, W Löscher, A Vezzani, AJ Becker… - The Lancet …, 2016 - thelancet.com
Over 50 million people worldwide have epilepsy. In nearly 30% of these cases, epilepsy
remains unsatisfactorily controlled despite the availability of over 20 antiepileptic drugs …

Viral infections and their relationship to neurological disorders

J Wouk, DZ Rechenchoski, BCD Rodrigues… - Archives of …, 2021 - Springer
The chronic dysfunction of neuronal cells, both central and peripheral, a characteristic of
neurological disorders, may be caused by irreversible damage and cell death. In 2016, more …

EAN consensus review on prevention, diagnosis and management of tick‐borne encephalitis

P Taba, E Schmutzhard, P Forsberg… - European journal of …, 2017 - Wiley Online Library
Background and purpose Tick‐borne encephalitis (TBE) is an infection of the central
nervous system (CNS) caused by tick‐borne encephalitis virus (TBEV) and transmitted by …