Immune reconstitution inflammatory syndrome in HIV-infected patients
NF Walker, J Scriven, G Meintjes… - HIV/AIDS-Research and …, 2015 - Taylor & Francis
Access to antiretroviral therapy (ART) is improving worldwide. Immune reconstitution
inflammatory syndrome (IRIS) is a common complication of ART initiation. In this review, we …
inflammatory syndrome (IRIS) is a common complication of ART initiation. In this review, we …
The Immune Response to Mycobacterium tuberculosis in HIV-1-Coinfected Persons
Globally, about 36.7 million people were living with HIV infection at the end of 2015. The
most frequent infection co-occurring with HIV-1 is Mycobacterium tuberculosis—374,000 …
most frequent infection co-occurring with HIV-1 is Mycobacterium tuberculosis—374,000 …
Prednisone for the prevention of paradoxical tuberculosis-associated IRIS
G Meintjes, C Stek, L Blumenthal… - … England Journal of …, 2018 - Mass Medical Soc
Background Early initiation of antiretroviral therapy (ART) in human immunodeficiency virus
(HIV)–infected patients who have tuberculosis reduces mortality among patients with low …
(HIV)–infected patients who have tuberculosis reduces mortality among patients with low …
HIV infection and immune activation: the role of coinfections
A Boulougoura, I Sereti - Current Opinion in HIV and AIDS, 2016 - journals.lww.com
Better understanding of the role of opportunistic infections at ART initiation and IRIS
pathogenesis will assist in improved strategies for prevention and treatment. The long-term …
pathogenesis will assist in improved strategies for prevention and treatment. The long-term …
Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by Mycobacterium tuberculosis in Infected Macrophages
Lysosomal cathepsin B (CTSB) has been proposed to play a role in the induction of acute
inflammation. We hypothesised that the presence of active CTSB in the cytosol is crucial for …
inflammation. We hypothesised that the presence of active CTSB in the cytosol is crucial for …
Tuberculosis IRIS: pathogenesis, presentation, and management across the spectrum of disease
CM Quinn, V Poplin, J Kasibante, K Yuquimpo… - Life, 2020 - mdpi.com
Antiretroviral therapy (ART), while essential in combatting tuberculosis (TB) and HIV
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …
coinfection, is often complicated by the TB-associated immune reconstitution inflammatory …
[HTML][HTML] Tuberculosis-immune reconstitution inflammatory syndrome
M Lanzafame, S Vento - Journal of Clinical Tuberculosis and Other …, 2016 - Elsevier
Tuberculosis-immune reconstitution inflammatory syndrome is an excessive immune
response against Mycobacterium tuberculosis that may occur in either HIV-infected or …
response against Mycobacterium tuberculosis that may occur in either HIV-infected or …
Mycobacterial Antigen Driven Activation of CD14++CD16− Monocytes Is a Predictor of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome
Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-
IRIS) is an aberrant inflammatory response occurring in a subset of TB-HIV co-infected …
IRIS) is an aberrant inflammatory response occurring in a subset of TB-HIV co-infected …
Management of active tuberculosis in adults with HIV
Every year, about 1 million people living with HIV worldwide develop tuberculosis. Although
the drug regimens used to treat tuberculosis in these patients are the same as those used in …
the drug regimens used to treat tuberculosis in these patients are the same as those used in …
Paradoxical TB-IRIS in HIV-infected adults: a systematic review and meta-analysis
PE Namale, LH Abdullahi, S Fine… - Future …, 2015 - Taylor & Francis
Paradoxical tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS) was first
described almost two decades ago. We undertook this systematic review and meta-analysis …
described almost two decades ago. We undertook this systematic review and meta-analysis …