Long non-coding RNAs (lncRNAs) outnumber protein-coding transcripts, but their functions
remain largely unknown. In this Review, we discuss the emerging roles of lncRNAs in the …

Expansion and activation of fibroblasts following cardiac injury is important for repair but
may also contribute to fibrosis, remodeling, and dysfunction. The authors discuss the …

Long non-coding RNAs (lncRNAs) have significant functions in a wide range of important
biological processes. Although the number of known human lncRNAs has dramatically …

We recently developed fluorescence-activated cell sorting (FACS)-based methods to purify
morphologically and functionally discrete populations of cells, each representing specific …

High throughput single-cell RNA-seq has been successfully implemented to dissect the
cellular and molecular features underlying hematopoiesis. However, an elaborate and …

Thousands of genes encoding long noncoding RNAs (lncRNAs) have been identified in all
vertebrate genomes thus far examined. The list of lncRNAs partaking in arguably important …

Long non-coding (lnc) RNAs can regulate gene expression and protein functions. However,
the proportion of lncRNAs with biological activities among the thousands expressed in …

MicroRNA (miRNA) have gained widespread attention for their role in diverse vascular
processes including angiogenesis, apoptosis, proliferation, and migration. Despite great …

Long noncoding RNAs (lncRNAs) are increasingly recognized as vital components of gene
programs controlling cell differentiation and function. Central to their functions is an ability to …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …