Pre-eclampsia and fetal growth restriction arise from disorders of placental development and
have some shared mechanistic features. Initiation is often rooted in the maldevelopment of a …

Each month during a woman's reproductive years, the endometrium undergoes vast
changes to prepare for a potential pregnancy. Diseases of the endometrium arise for …

The placenta has evolved to support the development of the embryo and fetus during the
different intrauterine periods of life. By necessity, its development must precede that of the …

The human endometrium is essential in providing the site for implantation and maintaining
the growth and survival of the conceptus. An unreceptive endometrium and disrupted …

Background The human endometrium undergoes recurring cycles of growth, differentiation,
and breakdown in response to sex hormones. Dysregulation of epithelial-stromal …

The uterus is vital for successful reproduction in mammals, and two different types of
epithelia (luminal and glandular) are essential for embryo implantation and pregnancy …

Bidirectional communication between the developing conceptus and endometrium is
essential for pregnancy recognition and establishment in ruminants. We dissect the …

Decidualization is an intricate biological process in which extensive remodeling of the
endometrium occurs to support the development of an implanting blastocyst. However, the …

The presence of granulated lymphocytes in the human uterine mucosa, known as decidua
during pregnancy, or endometrium otherwise, was first noted in the nineteenth century, but it …

The uterine luminal epithelium (LE) is the first maternal contact for an implanting embryo.
Intrauterine fluid resorption, cessation of LE proliferation and apoptosis, and LE structural …