[HTML][HTML] The 2016 World Health Organization classification of tumors of the central nervous system: a summary
Abstract The 2016 World Health Organization Classification of Tumors of the Central
Nervous System is both a conceptual and practical advance over its 2007 predecessor. For …
Nervous System is both a conceptual and practical advance over its 2007 predecessor. For …
Characterization of gliomas: from morphology to molecules
SP Ferris, JW Hofmann, DA Solomon, A Perry - Virchows Archiv, 2017 - Springer
This article reviews the histologic and molecular characterization of gliomas, including the
new “integrated diagnoses” of the World Health Organization Classification, 2016 edition …
new “integrated diagnoses” of the World Health Organization Classification, 2016 edition …
Artificial-intelligence-based molecular classification of diffuse gliomas using rapid, label-free optical imaging
Molecular classification has transformed the management of brain tumors by enabling more
accurate prognostication and personalized treatment. However, timely molecular diagnostic …
accurate prognostication and personalized treatment. However, timely molecular diagnostic …
Clinical practice guidelines for the management of adult diffuse gliomas
To follow the revision of the fourth edition of WHO classification and the recent progress on
the management of diffuse gliomas, the joint guideline committee of Chinese Glioma …
the management of diffuse gliomas, the joint guideline committee of Chinese Glioma …
Mutant IDH1 and seizures in patients with glioma
H Chen, J Judkins, C Thomas, M Wu, L Khoury… - Neurology, 2017 - AAN Enterprises
Objective: Because the d-2-hydroxyglutarate (D2HG) product of mutant isocitrate
dehydrogenase 1 (IDH1mut) is released by tumor cells into the microenvironment and is …
dehydrogenase 1 (IDH1mut) is released by tumor cells into the microenvironment and is …
[HTML][HTML] Isocitrate dehydrogenase (IDH) status prediction in histopathology images of gliomas using deep learning
Mutations in isocitrate dehydrogenase genes IDH1 and IDH2 are frequently found in diffuse
and anaplastic astrocytic and oligodendroglial tumours as well as in secondary …
and anaplastic astrocytic and oligodendroglial tumours as well as in secondary …
Efficacy of laser interstitial thermal therapy (LITT) for newly diagnosed and recurrent IDH wild-type glioblastoma
Background Treatment options for unresectable new and recurrent glioblastoma remain
limited. Laser ablation has demonstrated safety as a surgical approach to treating primary …
limited. Laser ablation has demonstrated safety as a surgical approach to treating primary …
Molecular classification of gliomas
The identification of distinct genetic and epigenetic profiles in different types of gliomas has
revealed novel diagnostic, prognostic, and predictive molecular biomarkers for refinement of …
revealed novel diagnostic, prognostic, and predictive molecular biomarkers for refinement of …
Improving the noninvasive classification of glioma genetic subtype with deep learning and diffusion-weighted imaging
Background Diagnostic classification of diffuse gliomas now requires an assessment of
molecular features, often including IDH-mutation and 1p19q-codeletion status. Because …
molecular features, often including IDH-mutation and 1p19q-codeletion status. Because …
[HTML][HTML] Applications of molecular neuro-oncology-a review of diffuse glioma integrated diagnosis and emerging molecular entities
MD Wood, AM Halfpenny, SR Moore - Diagnostic pathology, 2019 - Springer
Insights into the molecular underpinnings of primary central nervous system tumors have
radically changed the approach to tumor diagnosis and classification. Diagnostic emphasis …
radically changed the approach to tumor diagnosis and classification. Diagnostic emphasis …