Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …
dynamic properties and nanoscale control. These nanostructures enable complex …
Promoting apoptosis, a promising way to treat breast cancer with natural products: A comprehensive review
L Yuan, Y Cai, L Zhang, S Liu, P Li, X Li - Frontiers in pharmacology, 2022 - frontiersin.org
Breast cancer is one of the top-ranked malignant carcinomas associated with morbidity and
mortality in women worldwide. Chemotherapy is one of the main approaches to breast …
mortality in women worldwide. Chemotherapy is one of the main approaches to breast …
Advanced applications of DNA nanostructures dominated by DNA origami in antitumor drug delivery
Y Zhang, X Tian, Z Wang, H Wang, F Liu… - Frontiers in Molecular …, 2023 - frontiersin.org
DNA origami is a cutting-edge DNA self-assembly technique that neatly folds DNA strands
and creates specific structures based on the complementary base pairing principle. These …
and creates specific structures based on the complementary base pairing principle. These …
Current understanding of biological interactions and processing of dna origami nanostructures: role of machine learning and implications in drug delivery
DNA origami has emerged as an exciting avenue that provides a versatile two and three-
dimensional DNA-based platform for nanomedicine and drug delivery applications. Their …
dimensional DNA-based platform for nanomedicine and drug delivery applications. Their …
Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales
DNA origami technology enables the precise assembly of well-defined two-dimensional and
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …
DNA-functionalized gold nanorods for perioperative optical imaging and photothermal therapy of triple-negative breast cancer
Targeted imaging and therapy for triple-negative breast cancer (TNBC) in the perioperative
period are imperative for better disease management and improved life expectancy. Still …
period are imperative for better disease management and improved life expectancy. Still …
Recent advances in using folate receptor 1 (FOLR1) for cancer diagnosis and treatment, with an emphasis on cancers that affect women
P Varaganti, V Buddolla, BA Lakshmi, YJ Kim - Life Sciences, 2023 - Elsevier
A glycosylphosphatidylinositol (GPI)-anchored glycoprotein called the folate receptor 1
(FOLR1) facilitates the transportation of folate by mediating receptor-mediated endocytosis …
(FOLR1) facilitates the transportation of folate by mediating receptor-mediated endocytosis …
DNA nanodevice-based drug delivery systems
C Guan, X Zhu, C Feng - Biomolecules, 2021 - mdpi.com
DNA, a natural biological material, has become an ideal choice for biomedical applications,
mainly owing to its good biocompatibility, ease of synthesis, modifiability, and especially …
mainly owing to its good biocompatibility, ease of synthesis, modifiability, and especially …
Functionalized-DNA nanostructures as potential targeted drug delivery systems for cancer therapy
Seeman's pioneer idea has led to the foundation of DNA nanostructures, resulting in a
remarkable advancement in DNA nanotechnology. Over the last few decades, remarkable …
remarkable advancement in DNA nanotechnology. Over the last few decades, remarkable …
[HTML][HTML] Identification and Characterization of Fully Human FOLR1-Targeting CAR T Cells for the Treatment of Ovarian Cancer
M Bethke, P Abramowski, M Droste, A Felsberger… - Cells, 2024 - mdpi.com
CAR T cell therapy has been an effective treatment option for hematological malignancies.
However, the therapeutic potential of CAR T cells can be reduced by several constraints …
However, the therapeutic potential of CAR T cells can be reduced by several constraints …