SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …

TMPRSS2 is a type II transmembrane protease with broad expression in epithelial cells of
the respiratory and gastrointestinal tract, the prostate, and other organs. Although the …

SARS-CoV-2 is a respiratory pathogen and primarily infects the airway epithelium. As our
knowledge about innate immune factors of the respiratory tract against SARS-CoV-2 is …

Neutrophil extracellular traps (NETs), built from mitochondrial or nuclear DNA, proteinases,
and histones, entrap and eliminate pathogens in the course of bacterial or viral infections …

The ongoing pandemic illustrates limited therapeutic options for controlling SARS-CoV-2
infections, calling a need for additional therapeutic targets. The viral spike S glycoprotein …

Although many studies have been exploring the mechanisms driving NETs formation, much
less attention has been paid to the degradation and elimination of these structures. The …

Neutrophils are recognized as important circulating effector cells in the pathophysiology of
severe coronavirus disease 2019 (COVID-19). However, their role within the inflamed lungs …

ABSTRACT Introduction Coronavirus disease 2019 (COVID-19) is an infectious disease
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …

The COVID-19 pandemic, caused by SARS-CoV-2, has had a huge impact on global health.
To respond to rapidly mutating viruses and to prepare for the next pandemic, there is an …

Background COVID-19 infection has raised multiple concerns in pregnant mothers; many
questioned the risk of vertical transmission and the implication on the feto-maternal …