Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
Abstract 'Reactive oxygen species'(ROS) is an umbrella term for an array of derivatives of
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
molecular oxygen that occur as a normal attribute of aerobic life. Elevated formation of the …
[HTML][HTML] Oxidative eustress: On constant alert for redox homeostasis
H Sies - Redox Biology, 2021 - Elsevier
In the open metabolic system, redox-related signaling requires continuous monitoring and
fine-tuning of the steady-state redox set point. The ongoing oxidative metabolism is a …
fine-tuning of the steady-state redox set point. The ongoing oxidative metabolism is a …
Manmade electromagnetic fields and oxidative stress—biological effects and consequences for health
D Schuermann, M Mevissen - International journal of molecular sciences, 2021 - mdpi.com
Concomitant with the ever-expanding use of electrical appliances and mobile
communication systems, public and occupational exposure to electromagnetic fields (EMF) …
communication systems, public and occupational exposure to electromagnetic fields (EMF) …
The interplay between intracellular iron homeostasis and neuroinflammation in neurodegenerative diseases
J Lee, DH Hyun - Antioxidants, 2023 - mdpi.com
Iron is essential for life. Many enzymes require iron for appropriate function. However,
dysregulation of intracellular iron homeostasis produces excessive reactive oxygen species …
dysregulation of intracellular iron homeostasis produces excessive reactive oxygen species …
Connecting the “dots”: from free radical lipid autoxidation to cell pathology and disease
Our understanding of lipid peroxidation in biology and medicine is rapidly evolving, as it is
increasingly implicated in various diseases but also recognized as a key part of normal cell …
increasingly implicated in various diseases but also recognized as a key part of normal cell …
Targeting oxidative stress involved in endometriosis and its pain
L Clower, T Fleshman, WJ Geldenhuys, N Santanam - Biomolecules, 2022 - mdpi.com
Endometriosis is a common gynecological disorder seen in women and is characterized by
chronic pelvic pain and infertility. This disorder is becoming more prevalent with increased …
chronic pelvic pain and infertility. This disorder is becoming more prevalent with increased …
Artesunate inhibits the cell growth in colorectal cancer by promoting ROS-dependent cell senescence and autophagy
Z Huang, S Gan, X Zhuang, Y Chen, L Lu, Y Wang… - Cells, 2022 - mdpi.com
Although artesunate has been reported to be a promising candidate for colorectal cancer
(CRC) treatment, the underlying mechanisms and molecular targets of artesunate are yet to …
(CRC) treatment, the underlying mechanisms and molecular targets of artesunate are yet to …
Reactive oxygen species: angels and demons in the life of a neuron
K Biswas, K Alexander, MM Francis - NeuroSci, 2022 - mdpi.com
Reactive oxygen species (ROS) have emerged as regulators of key processes supporting
neuronal growth, function, and plasticity across lifespan. At normal physiological levels, ROS …
neuronal growth, function, and plasticity across lifespan. At normal physiological levels, ROS …
[HTML][HTML] Nox4 as a novel therapeutic target for diabetic vascular complications
D Wang, J Li, G Luo, J Zhou, N Wang, S Wang, R Zhao… - Redox Biology, 2023 - Elsevier
Diabetic vascular complications can affect both microvascular and macrovascular. Diabetic
microvascular complications, such as diabetic nephropathy, diabetic retinopathy, diabetic …
microvascular complications, such as diabetic nephropathy, diabetic retinopathy, diabetic …
Endoplasmic reticulum-mitochondria contacts modulate reactive oxygen species-mediated signaling and oxidative stress in brain disorders: The key role of sigma-1 …
R Resende, T Fernandes, AC Pereira… - Antioxidants & Redox …, 2022 - liebertpub.com
Significance: Mitochondria-Associated Membranes (MAMs) are highly dynamic endoplasmic
reticulum (ER)-mitochondria contact sites that, due to the transfer of lipids and Ca2+ …
reticulum (ER)-mitochondria contact sites that, due to the transfer of lipids and Ca2+ …