1, 3, 4‐Thiadiazole and its derivatives: A review on recent progress in biological activities

AK Jain, S Sharma, A Vaidya… - Chemical biology & …, 2013 - Wiley Online Library
The 1, 3, 4‐thiadiazole nucleus is one of the most important and well‐known heterocyclic
nuclei, which is a common and integral feature of a variety of natural products and medicinal …

Triazole analogues as potential pharmacological agents: A brief review

S Kumar, SL Khokra, A Yadav - Future Journal of Pharmaceutical …, 2021 - Springer
Background A large number of studies have recently reported that, because of their
significant biological and pharmacological properties, heterocyclic compounds and their …

2-Amino-1, 3, 4-thiadiazole as a potential scaffold for promising antimicrobial agents

G Serban, O Stanasel, E Serban… - Drug design, development …, 2018 - Taylor & Francis
Pathogenic microorganisms are causative agents for different types of serious and even
lethal infectious diseases. Despite advancements in medication, bacterial and fungal …

Recent advances bioactive 1, 2, 4-triazole-3-thiones

ŞG Küçükgüzel, P Çıkla-Süzgün - European journal of medicinal chemistry, 2015 - Elsevier
Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …

A review on 'triazoles': Their chemistry, synthesis and pharmacological potentials

D Dixit, PK Verma, RK Marwaha - Journal of the Iranian Chemical Society, 2021 - Springer
Heterocyclic compounds are cyclic compounds as an atom of ring members with at least two
different elements. In the five-membered aromatic azole chain, triazole compounds …

[PDF][PDF] Thiadiazoles: progress report on biological activities

N Siddiqui, P Ahuja, W Ahsan, SN Pandeya… - J Chem Pharm …, 2009 - academia.edu
Several five membered aromatic systems having three heteroatoms at symmetrical positions
such as thiadiazoles have been studied extensively owing to their interesting …

Synthetic methods, chemistry, and the anticonvulsant activity of thiadiazoles

B Sharma, A Verma, S Prajapati… - International journal of …, 2013 - Wiley Online Library
The chemistry of heterocyclic compounds has been an interesting field of study for a long
time. Heterocyclic nucleus 1, 3, 4‐thiadiazole constitutes an important class of compounds …

Improvement of antibacterial activity of some sulfa drugs through linkage to certain phthalazin-1 (2H)-one scaffolds

HS Ibrahim, WM Eldehna, HA Abdel-Aziz… - European journal of …, 2014 - Elsevier
RAB1 5 is a lead antibacterial agent in which trimethoprim is linked to phthalazine moiety.
Similarly, our strategy in this research depends on the interconnection between some sulfa …

Recent advances in the synthesis of biologically active cinnoline, phthalazine and quinoxaline derivatives

Y Taek Han, JW Jung, NJ Kim - Current Organic Chemistry, 2017 - ingentaconnect.com
In the recent decades, N-heterocycles are widely used as versatile scaffolds for the
development of biologically active compounds and considered as one of the privileged …

Antifungal effect of 4-arylthiosemicarbazides against Candida species. Search for molecular basis of antifungal activity of thiosemicarbazide derivatives

A Siwek, J Stefańska, K Dzitko, A Ruszczak - Journal of molecular …, 2012 - Springer
The in vitro antifungal potency of six series of 4-arylthiosemicarbazides was evaluated. Two
isoquinoline derivatives with an ortho-methoxy or ortho-methyl group at the phenyl ring were …