The envelope layers of mycobacteria with reference to their pathogenicity

M Daffé, P Draper - Advances in microbial physiology, 1997 - Elsevier
The review discusses current knowledge of the biosynthesis, composition and arrangement
of the mycobacterial envelope, describes the biological activities of the constituents and …

Glycan Reader is improved to recognize most sugar types and chemical modifications in the Protein Data Bank

SJ Park, J Lee, DS Patel, H Ma, HS Lee, S Jo… - …, 2017 - academic.oup.com
Motivation Glycans play a central role in many essential biological processes. Glycan
Reader was originally developed to simplify the reading of Protein Data Bank (PDB) files …

Mycobacterial glycoconjugates as vaccine candidates against tuberculosis

G Källenius, A Pawlowski, B Hamasur… - Trends in microbiology, 2008 - cell.com
There is an urgent need for an efficient vaccine against tuberculosis. Here, we explore the
potential role of carbohydrate antigens as part of a new tuberculosis vaccine. Emphasis is …

The CD1d‐binding glycolipid α‐galactosylceramide enhances humoral immunity to T‐dependent and T‐independent antigen in a CD1d‐dependent manner

GA Lang, MA Exley, ML Lang - Immunology, 2006 - Wiley Online Library
Specific interaction of class II/peptide with the T‐cell receptor (TCR) expressed by class II‐
restricted CD4+ T helper (Th) cells is essential for in vivo production of antibodies reactive …

The carbohydrate-and lipid-containing cell wall of mycobacteria, phenolic glycolipids: structure and immunological properties

G Puzo - Critical reviews in microbiology, 1990 - Taylor & Francis
Phenolic glycolipids were first discovered as cell-wall constituents of M. bovis, M. bovis BCG,
M. marinum, and M. kansasii. Recently, such compounds were also isolated from M. leprae …

Methods of isolating CD1-presented antigens, vaccines comprising CD1-presented antigens, and cell lines for use in said methods

SA Porcelli, MB Brenner, EM Beckman - US Patent 5,679,347, 1997 - Google Patents
US5679347A - Methods of isolating CD1-presented antigens, vaccines comprising CD1-presented
antigens, and cell lines for use in said methods - Google Patents US5679347A - Methods of …

Assessment of different formulations of oral Mycobacterium bovis Bacille Calmette-Guérin (BCG) vaccine in rodent models for immunogenicity and protection against …

S Clark, ML Cross, A Smith, P Court, J Vipond… - Vaccine, 2008 - Elsevier
Bovine tuberculosis (bTB) caused by infection with Mycobacterium bovis is causing
considerable economic loss to farmers and Government in the United Kingdom as its …

Do CD1-Restricted T Cells Contribute to Antibody-Mediated Immunity against Mycobacterium tuberculosis?

ML Lang, A Glatman-Freedman - Infection and immunity, 2006 - Am Soc Microbiol
More than 100 years after the discovery of the tubercle bacillus by Robert Koch (43) and
approximately 50 years after the introduction of effective antimycobacterial therapeutic …

BCR targeting of biotin-α-galactosylceramide leads to enhanced presentation on CD1d and requires transport of BCR to CD1d-containing endocytic compartments

GA Lang, PA Illarionov… - International …, 2005 - academic.oup.com
CD1d is a non-polymorphic MHC class I-related protein that binds and presents glycolipid
antigens to T cell antigen receptors expressed by NK-like T (NKT) cells. CD1d-dependent …

Phosphatidylinositol mannosides are efficient mucosal adjuvants

NA Parlane, M Denis, WB Severn… - Immunological …, 2008 - Taylor & Francis
The development of defined sub-unit vaccines requires the inclusion in the vaccine of an
immunological adjuvant. The most important property of adjuvants for vaccines aimed at …