Novel development of 5-aminolevurinic acid (ALA) in cancer diagnoses and therapy

M Ishizuka, F Abe, Y Sano, K Takahashi, K Inoue… - International …, 2011 - Elsevier
Early detection and intervention are needed for optimal outcomes in cancer therapy.
Improvements in diagnostic technology, including endoscopy, photodynamic diagnosis …

Fluorescence-guided surgery: a review on timing and use in brain tumor surgery

AJ Schupper, M Rao, N Mohammadi, R Baron… - Frontiers in …, 2021 - frontiersin.org
Fluorescence-guided surgery (FGS) allows surgeons to have improved visualization of
tumor tissue in the operating room, enabling maximal safe resection of malignant brain …

Combating melanoma: The use of photodynamic therapy as a novel, adjuvant therapeutic tool

LM Davids, B Kleemann - Cancer treatment reviews, 2011 - Elsevier
Metastatic malignant melanoma remains one of the most dreaded skin cancers worldwide.
Numerous factors contribute to its resistance to hosts of treatment regimes and despite …

Evaluation of photodynamic therapy efficiency using an in vitro three-dimensional microfluidic breast cancer tissue model

Y Yang, X Yang, J Zou, C Jia, Y Hu, H Du, H Wang - Lab on a Chip, 2015 - pubs.rsc.org
In recognition of the limitations of monolayer cell cultures and resource-intensive animal
studies, a microfluidic culture system was developed for creation of physiologically relevant …

MPPa-PDT suppresses breast tumor migration/invasion by inhibiting Akt-NF-κB-dependent MMP-9 expression via ROS

L Huang, H Lin, Q Chen, L Yu, D Bai - BMC cancer, 2019 - Springer
Background Breast cancer is one of the most commonly diagnosed cancers in women, with
high morbidity and mortality. Tumor metastasis is implicated in most breast cancer deaths; …

[HTML][HTML] Fluorescence in neurosurgery: its diagnostic and therapeutic use. Review of the literature

C Ewelt, A Nemes, V Senner, J Wölfer… - … of Photochemistry and …, 2015 - Elsevier
Fluorescent agents, eg 5-aminolevulinic acid (5-ALA), fluorescein and indocyanine green
(ICG) are in common use in neurosurgery for tumor resection and neurovascular surgery …

Electroporation and lipid nanoparticles with cyanine IR-780 and flavonoids as efficient vectors to enhanced drug delivery in colon cancer

J Kulbacka, A Pucek, M Kotulska… - …, 2016 - Elsevier
Nanocarriers and electroporation (also named electropermeabilization) are convenient
methods to increase drug transport. In the current study, we present an effective support of …

Targets and mechanisms of photodynamic therapy in lung cancer cells: a brief overview

A Chiaviello, I Postiglione, G Palumbo - Cancers, 2011 - mdpi.com
Lung cancer remains one of the most common cancer-related causes of death. This type of
cancer typically develops over a period of many years, and if detected at an early enough …

Susceptibility and resistance mechanisms during photodynamic therapy of melanoma

XY Li, LC Tan, LW Dong, WQ Zhang, XX Shen… - Frontiers in …, 2020 - frontiersin.org
Melanoma is the most aggressive malignant skin tumor and arises from melanocytes. The
resistance of melanoma cells to various treatments results in rapid tumor growth and high …

[HTML][HTML] Plasma-derived exosomes reverse epithelial-to-mesenchymal transition after photodynamic therapy of patients with head and neck cancer

MN Theodoraki, SS Yerneni, C Brunner… - …, 2018 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a palliative treatment option for head and neck squamous
cell carcinoma (HNSCC) patients which induces local inflammation and alters tumor cell …