Leukocyte trafficking to the small and large intestines is tightly controlled to maintain
intestinal immune homeostasis, mediate immune responses, and regulate inflammation. A …

Chemerin, a chemoattractant protein and adipokine, has been identified as the endogenous
ligand for a G protein–coupled receptor encoded by the gene CMKLR1 (also known as …

Introduction: Inflammatory bowel disease (IBD) is a systemic disease with immune
abnormalities that can affect the entire digestive tract. A high percentage of patients with IBD …

Fat tissue was initially described for its endocrine and metabolic function. Over the last two
decades increasing evidence indicated a close interaction with the immune system. Partly …

In the last decade, there has been growing interest in the pathological involvement of
hypertrophic mesenteric fat attached to the serosa of the inflamed intestinal segments …

It is already well-known that visceral adipose tissue is inseparably related to the
pathogenesis, activity, and general outcome of inflammatory bowel disease (IBD). We are …

Though historically regarded as an inert energy store, adipose tissue is a complex
endocrine organ, which is increasingly implicated in the pathogenesis of inflammatory bowel …

For poultry producers, chronic low-grade intestinal inflammation has a negative impact on
productivity by impairing nutrient absorption and allocation of nutrients for growth …

Rationale: Inflammatory bowel disease (IBD) is a chronic disorder characterized by
persistent inflammation of the gastrointestinal tract. Due to the elusive causes and complex …

Although the phenomenon of hypertrophied adipose tissue surrounding inflamed bowel
segments in Crohn's disease has been described since 1932, the mechanisms mediating …