Ethics of DNA research on human remains: five globally applicable guidelines

S Alpaslan-Roodenberg, D Anthony, H Babiker… - Nature, 2021 - nature.com
We are a group of archaeologists, anthropologists, curators and geneticists representing
diverse global communities and 31 countries. All of us met in a virtual workshop dedicated to …

Artificial intelligence, healthcare, clinical genomics, and pharmacogenomics approaches in precision medicine

H Abdelhalim, A Berber, M Lodi, R Jain, A Nair… - Frontiers in …, 2022 - frontiersin.org
Precision medicine has greatly aided in improving health outcomes using earlier diagnosis
and better prognosis for chronic diseases. It makes use of clinical data associated with the …

The sequences of 150,119 genomes in the UK Biobank

BV Halldorsson, HP Eggertsson, KHS Moore… - Nature, 2022 - nature.com
Detailed knowledge of how diversity in the sequence of the human genome affects
phenotypic diversity depends on a comprehensive and reliable characterization of both …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

The GenomeAsia 100K Project enables genetic discoveries across Asia

Nature, 2019 - nature.com
The underrepresentation of non-Europeans in human genetic studies so far has limited the
diversity of individuals in genomic datasets and led to reduced medical relevance for a large …

[图书][B] Who we are and how we got here: Ancient DNA and the new science of the human past

D Reich - 2018 - books.google.com
The past few years have witnessed a revolution in our ability to obtain DNA from ancient
humans. This important new data has added to our knowledge from archaeology and …

The formation of human populations in South and Central Asia

VM Narasimhan, N Patterson, P Moorjani, N Rohland… - Science, 2019 - science.org
RATIONALE To elucidate the extent to which the major cultural transformations of farming,
pastoralism, and shifts in the distribution of languages in Eurasia were accompanied by …

The deep population history of northern East Asia from the Late Pleistocene to the Holocene

X Mao, H Zhang, S Qiao, Y Liu, F Chang, P Xie… - Cell, 2021 - cell.com
Summary Northern East Asia was inhabited by modern humans as early as 40 thousand
years ago (ka), as demonstrated by the Tianyuan individual. Using genome-wide data …

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

A Tin, J Marten, VL Halperin Kuhns, Y Li, M Wuttke… - Nature …, 2019 - nature.com
Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via
poorly understood mechanisms. We performed a trans-ancestry genome-wide association …

Ancient genomes document multiple waves of migration in Southeast Asian prehistory

M Lipson, O Cheronet, S Mallick, N Rohland… - Science, 2018 - science.org
Southeast Asia is home to rich human genetic and linguistic diversity, but the details of past
population movements in the region are not well known. Here, we report genome-wide …