Excessive abnormal angiogenesis plays a pivotal role in tumor progression and is a
hallmark of solid tumors. This process is driven by an imbalance between pro-and anti …

Abstract The US Food and Drug Administration (FDA) Adverse Event Reporting System
(FAERS, formerly AERS) is a database that contains information on adverse event and …

Clear cell renal cell carcinoma (ccRCC) is the most prevalent histological subtype of kidney
cancer, which is prone to metastasis, recurrence, and resistance to radiotherapy and …

Cancer, a life threatening disease adversely affects huge population worldwide. Naturally
derived drug discovery has emerged as a potential pathway in search of anticancers …

The search for an effective drug to treat oncological diseases, which have become the main
scourge of mankind, has generated a lot of methods for studying this affliction. It has also …

Retinopathy of prematurity (ROP), a retinal vascular disease of premature infants, continues
to be a major cause of preventable childhood blindness all over the world. The incidence of …

The early stages of angiogenesis can be divided into three steps: endothelial cell
proliferation, migration, and tube formation. Vascular endothelial growth factor (VEGF) is …

The mPEBev is an anticancer regimen which combines a chemotherapy doublet, based on
cisplatin and oral etoposide (mPE), with bevacizumab (mPEBev), a mAb targeting the …

Background Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting toxicity
of paclitaxel, with no reliable method to identify at-risk patients. We investigated the …

Diabetes is a chronic metabolic disease characterized by an excess of glucose in the blood.
If the constant sugar level is not managed correctly in diabetic patients, it may lead to …