Macrogenomic engineering via modulation of the scaling of chromatin packing density
LM Almassalha, GM Bauer, W Wu… - Nature biomedical …, 2017 - nature.com
Many human diseases result from the dysregulation of the complex interactions between
tens to thousands of genes. However, approaches for the transcriptional modulation of many …
tens to thousands of genes. However, approaches for the transcriptional modulation of many …
Disordered chromatin packing regulates phenotypic plasticity
Three-dimensional supranucleosomal chromatin packing plays a profound role in
modulating gene expression by regulating transcription reactions through mechanisms such …
modulating gene expression by regulating transcription reactions through mechanisms such …
[HTML][HTML] Uridine as a protector against hypoxia-induced lung injury
The effect of the activation of the mitochondrial ATP-dependent potassium channel
(mitoKATP) on the ultrastructure of rat lung in acute hypoxic hypoxia (7% of oxygen in …
(mitoKATP) on the ultrastructure of rat lung in acute hypoxic hypoxia (7% of oxygen in …
Light scintillation in soft biological tissues
The applicability limits of the small complex phase perturbation (Rytov) theory for laser light
propagation in soft biological tissues have been tackled. We have found that for typical …
propagation in soft biological tissues have been tackled. We have found that for typical …
Measuring nanoscale chromatin heterogeneity with partial wave spectroscopic microscopy
Despite extensive research in the area, current understanding of the structural organization
of higher-order chromatin topology (between 20 and 200 nm) is limited due to a lack of …
of higher-order chromatin topology (between 20 and 200 nm) is limited due to a lack of …
Origins of subdiffractional contrast in optical coherence tomography
We demonstrate that OCT images quantify subdiffractional tissue structure. Optical
coherence tomography (OCT) measures stratified tissue morphology with spatial resolution …
coherence tomography (OCT) measures stratified tissue morphology with spatial resolution …
[HTML][HTML] Early increase in blood supply (EIBS) is associated with tumor risk in the Azoxymethane model of colon cancer
S Ruderman, A Eshein, V Valuckaite, U Dougherty… - BMC cancer, 2018 - Springer
Background The present study aimed to investigate the role of blood supply in early
tumorigenesis in colorectal cancer. We leveraged the renin angiotensin system (RAS) to …
tumorigenesis in colorectal cancer. We leveraged the renin angiotensin system (RAS) to …
[PDF][PDF] 人工制备生物颗粒结构对宽波段消光性能的影响
黄宝锟， 胡以华， 顾有林， 赵义正， 李乐， 赵欣颖 - 红外与激光工程, 2018 - researching.cn
为研究多态生物颗粒对目标探测等电磁设备的影响, 将制备出的絮状生物颗粒等效为子弹玫瑰花
型粒子, 构建不同分枝数目和分枝长度的生物颗粒, 采用离散偶极子近似法计算生物颗粒消光 …
型粒子, 构建不同分枝数目和分枝长度的生物颗粒, 采用离散偶极子近似法计算生物颗粒消光 …
Developments in Modeling and Analysis of Interferometric Spectroscopic Imaging
A Eid - 2021 - search.proquest.com
Optical microscopy is one of the most ubiquitous tools for functional imaging of biological
phenomena. While relatively non-destructive to living organisms, light microscopy's spatial …
phenomena. While relatively non-destructive to living organisms, light microscopy's spatial …
The Development and Applications of Multimodal Interferometric Imaging to Measure Nanoscale Structure and Macromolecular Motion
SJ Gladstein - 2019 - search.proquest.com
Chromatin, a complex nuclear structure comprised of DNA, histones, RNA, and other
nuclear proteins, is one of the most critical components within the cell because it houses the …
nuclear proteins, is one of the most critical components within the cell because it houses the …