[HTML][HTML] X-linked adrenoleukodystrophy: clinical, biochemical and pathogenetic aspects

J Berger, J Gärtner - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2006 - Elsevier
X-linked adrenoleukodystrophy (X-ALD) is a clinically heterogeneous disorder ranging from
the severe childhood cerebral form to asymptomatic persons. The overall incidence is 1 …

Very long chain fatty acids in higher animals—a review

A Poulos - Lipids, 1995 - Wiley Online Library
Fatty acids with greater than 22 carbon atoms (very long chain fatty acids, VLCFA) are
present in small amounts in most animal tissues. Saturated and monoenoic VLCFA are …

[HTML][HTML] Molecular breeding for introgression of fatty acid desaturase mutant alleles (ahFAD2A and ahFAD2B) enhances oil quality in high and low oil containing …

P Janila, MK Pandey, Y Shasidhar, MT Variath… - Plant Science, 2016 - Elsevier
High oleate peanuts have two marketable benefits, health benefits to consumers and
extended shelf life of peanut products. Two mutant alleles present on linkage group a09 …

Aldehyde dehydrogenase 3a2 protects AML cells from oxidative death and the synthetic lethality of ferroptosis inducers

RZ Yusuf, B Saez, A Sharda… - Blood, The Journal …, 2020 - ashpublications.org
Metabolic alterations in cancer represent convergent effects of oncogenic mutations. We
hypothesized that a metabolism-restricted genetic screen, comparing normal primary mouse …

A mouse model for X-linked adrenoleukodystrophy

JF Lu, AM Lawler, PA Watkins… - Proceedings of the …, 1997 - National Acad Sciences
X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder with impaired β-oxidation
of very long chain fatty acids (VLCFAs) and reduced function of peroxisomal very long chain …

A two-year trial of oleic and erucic acids (“Lorenzo's oil”) as treatment for adrenomyeloneuropathy

P Aubourg, C Adamsbaum… - … England Journal of …, 1993 - Mass Medical Soc
Background Adrenomyeloneuropathy is an X-linked recessive disorder characterized by
myelopathy, peripheral neuropathy, and cerebral demyelination, which develop in …

Follow-up of 89 asymptomatic patients with adrenoleukodystrophy treated with Lorenzo's oil

HW Moser, GV Raymond, SE Lu, LR Muenz… - Archives of …, 2005 - jamanetwork.com
Objectives To identify asymptomatic boys with X-linked adrenoleukodystrophy who have a
normal magnetic resonance image (MRI), and to assess the effect of 4: 1 glyceryl trioleate …

Advances in Crop Improvement and Delivery Research for Nutritional Quality and Health Benefits of Groundnut (Arachis hypogaea L.)

CO Ojiewo, P Janila, P Bhatnagar-Mathur… - Frontiers in Plant …, 2020 - frontiersin.org
Groundnut is an important global food and oil crop that underpins agriculture-dependent
livelihood strategies meeting food, nutrition, and income security. Aflatoxins, pose a major …

Adrenoleukodystrophy: phenotypic variability and implications for therapy

HW Moser, AB Moser, KD Smith… - Journal of inherited …, 1992 - Wiley Online Library
X‐linked adrenoleukodystrophy (ALD) is a relatively common disorder that shows a great
deal of phenotypic variability. Approximately half of the patients have the rapidly progressive …

[HTML][HTML] Sapindus mukorossi Gaertn. and its bioactive metabolite oleic acid impedes methicillin-resistant Staphylococcus aureus biofilm formation by down regulating …

A Selvaraj, A Valliammai, M Premika, A Priya… - Microbiological …, 2021 - Elsevier
Plants are boon to the mankind due to plenty of metabolites with medicinal values. Though
plants have traditionally been used to treat various diseases, their biological values are not …