Among the various immunological and non-immunological tumor-promoting activities of
myeloid-derived suppressor cells (MDSCs), their immunosuppressive capacity remains a …

Prostate cancer is the most commonly diagnosed cancer and the second leading cause of
cancer-related death among men in western countries. Androgen deprivation therapy (ADT) …

The landscape of cancer treatment has been transformed over the past decade by the
success of immune-targeting therapies. However, despite sipuleucel-T being the first-ever …

Our understanding of neuroendocrine prostate cancer (NEPC) has assumed a new
perspective in light of the recent advances in research. Although classical NEPC is rarely …

Mast cells (MCs) are crucial cells participating in both innate and adaptive immune
processes that play important roles in protecting human health and in the pathophysiology of …

Our understanding is limited concerning the tumor immune microenvironment of
inflammatory breast cancer (IBC), an aggressive form of primary cancer with low rates of …

Chimeric antigen receptor (CAR) T cell immunotherapy involves the genetic modification of
the patient's own T cells so that they specifically recognize and destroy tumour cells …

Abstract Interleukin (IL)-9 belongs to the IL-2Rγc chain family and is a multifunctional
cytokine that can regulate the function of many kinds of cells. It was originally identified as a …

Tumor cells express a high quantity of exosomes packaged with unique cargos under
hypoxia, an important characteristic feature in solid tumors. These hypoxic tumor-derived …

Tumor outcome is determined not only by cancer cell–intrinsic features but also by the
interaction between cancer cells and their microenvironment. There is great interest in tumor …